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Mydriasis

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February 13, 2023
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FDA accepts NDA for Nyxol drops for mydriasis reversal

The FDA accepted a new drug application for Nyxol for the reversal of pharmacologically induced mydriasis, according to a press release from Ocuphire Pharma.

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November 08, 2022
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Ocuphire enters global license agreement with Famy for Nyxol development

Ocuphire Pharma and FamyGen Life Sciences have entered into a global licensing agreement that will allow Famy to fund and commercialize the development of Nyxol eye drops in the U.S. as well as globally, according to a press release.

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November 07, 2022
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From one eye whisperer to another: A decade in review

I would like to congratulate Mitch Jackson on his 100th Premium Channel column in OSN. Mitch’s entertaining approach to presenting cutting-edge techniques and technology in premium refractive surgery has always matched his ebullient personality.

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July 18, 2022
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VIDEO: Phentolamine may be effective in reversing induced mydriasis

NEW YORK — In this Healio Video Perspective from the ASRS meeting, David S. Boyer, MD, discusses the results of the MIRA-2 and MIRA-3 studies investigating phentolamine as a treatment for reversing pharmacologically induced mydriasis.

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May 06, 2022
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‘I did, not I wish’: Mydriasis reversal will hasten return to real life

Three years ago, tragedy struck my family with the loss of my brother due to metastatic lung cancer.

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April 28, 2022
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Positive safety results reported for Nyxol in pediatric patients

Nyxol demonstrated positive results in a pediatric safety trial to reverse pharmacologically induced mydriasis, according to a press release from Ocuphire Pharma.

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April 20, 2022
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VIDEO: Nyxol trial shows positive results for mydriasis reversal

NEW YORK – A phase 3 FDA registration trial for Ocuphire Pharma’s Nyxol yielded positive topline results for the reversal of mydriasis, according to a company executive.

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March 29, 2022
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Nyxol meets primary endpoint in trial evaluating reversal of mydriasis

In a second phase 3 registration trial, Nyxol helped reverse pharmacologically induced mydriasis at 90 minutes, according to a press release from Ocuphire Pharma.

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May 19, 2021
3 min read
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Drop speeds reversal of pharmacologically induced mydriasis

Nyxol, an alpha 1/2 antagonist eye drop, helped reverse the effects of pharmacologically induced mydriasis in healthy subjects, according to a phase 3 study.

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April 13, 2021
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VIDEO: Drop accelerates mydriasis reversal, reduces dim light disturbances

In this video, Jay S. Pepose, MD, PhD, discusses research on new indications for the use of phentolamine for the rapid reversal of mydriasis after ocular examination and for the reduction of nocturnal visual disturbances.

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