Multisystem Inflammatory Syndrome

The severity of multisystem inflammatory syndrome in children decreased as the COVID-19 pandemic went on, and most children recovered to their preinfection health within 6 months, according to two recent studies.

Children hospitalized with SARS-CoV-2 or an inflammatory syndrome associated with SARS-CoV-2 infection who experience severe neurological manifestations may be at a higher risk for long-term impairment, a study found.

Nearly one in five patients diagnosed with multisystem inflammatory syndrome in children based on a 2020 definition would not be diagnosed with the illness using an updated definition, researchers reported in Pediatrics.

Children with obesity demonstrate a greater likelihood of shock, ICU admission and worse laboratory scores in multisystem inflammatory syndrome, but not Kawasaki disease, according to data published in JAMA Network Open.

Patients recovering from multisystem inflammatory syndrome in children should receive a cardiology follow-up, study findings reported in Pediatrics suggest.