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August 29, 2019
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Vistusertib fails to confer PFS benefit with fulvestrant for ER-positive breast cancer

Fulvestrant in combination with everolimus extended PFS significantly longer than fulvestrant with vistusertib or fulvestrant alone among women with hormone receptor-positive metastatic breast cancer, according to results of the randomized phase 2 MANTA trial published in JAMA Oncology.