Mpox

SAN FRANCISCO — Tecovirimat failed to reduce clade II mpox lesions, pain or viral clearance among participants in a study of the antiviral that was stopped early based on a futility analysis, according to data presented here.

In July of 2022, mpox was declared a Public Health Emergency of International Concern, or PHEIC, by WHO during a surge in infections that led to more than 100,000 cases in 122 countries.

There are two lines of research we are pursuing in our lab currently.

Waning smallpox immunity in the Democratic Republic of the Congo has contributed to a significant increase in mpox cases over the last 15 years, but a study suggests there are also other causes for the virus’ rise in prominence.

After consuming organic carrots infected with Escherichia coli, one person has died and 15 people have been hospitalized in a multistate outbreak of the disease.

The first known U.S. case of an mpox clade that has historically been more transmissible and deadly was detected in California in a person who had recently returned from travel to Eastern Africa, according to health officials.

An Iowa resident died of Lassa fever after returning home from travel to West Africa, according to Iowa health officials.

LOS ANGELES — Neutralizing antibodies against mpox generated by the Jynneos vaccine were short lived — lasting less than a year — if patients had never received a smallpox vaccine as children, researchers said.

LOS ANGELES — Interim data from a phase 2 clinical trial of the Jynneos mpox vaccine showed that it is safe and generates an antibody response in adolescents that is similar to the response seen in adults, researchers reported.

A study of people in the United Kingdom revealed that COVID-19 vaccination may reduce the risk for heart attack and stroke — possibly because the vaccine prevents the cardiovascular effects of SARS-CoV-2 infection, researchers said.