Motor Function
Givinostat improves range of motion, reduces decline of muscle function in DMD
Treatment with givinostat for ambulatory boys with Duchenne muscular dystrophy led to improved motion and reduced decline of muscle function and strength at 18 months, according to a poster at the 2024 MDA Clinical & Scientific Conference.
Zolgensma improves motor function at 52 weeks in spinal muscular atrophy
Treatment with Zolgensma improved motor function in a cohort of children with spinal muscular atrophy, according to a poster at the 2024 MDA Clinical & Scientific Conference.
In-home standing desk improved motor skills, quality of life in adults with Parkinson’s
CHICAGO — Use of an in-home therapy desk improved motor skills and balance and reduced sedentarism in adults with Parkinson’s disease, according to data at the International Association of Parkinsonism and Related Disorders World Congress.
Tributyrin linked to improved motor symptoms, inflammatory markers in Parkinson’s
CHICAGO — Tributyrin supplementation may have a beneficial effect on motor symptoms and inflammatory markers in Parkinson’s disease, according to data at the International Association of Parkinsonism and Related Disorders World Congress.
Viltolarsen shows long-term effectiveness, safety in Duchenne muscular dystrophy
Viltolarsen delayed disease progression over 4 years in children with Duchenne muscular dystrophy, with most treatment-emergent adverse events being mild or moderate, according to a poster at the 2023 MDA Clinical & Scientific Conference.
Positive interim data announced in phase 1/2 trial of gene therapy for Canavan disease
Myrtelle Inc. announced updated findings of the open-label phase 1/2 clinical trial of its recombinant adeno-associated virus vector-based investigational gene therapy for Canavan disease, a fatal genetic disorder in children.
Treatment with nusinersen improved motor function up to 5 years in infantile-onset SMA
Treatment with nusinersen led to continued and improved motor function up to 5 years after initial dose in infants with spinal muscular atrophy, according to a poster presented at the International Scientific Congress on Spinal Muscular Atrophy.
Early surgical decompression may improve motor function in central cord syndrome
Patients with central cord syndrome who underwent early surgical decompression had improved recovery in upper limb motor function at 1 year compared with patients who underwent late surgical decompression, according to published results.
Risdiplam over 24 months improved motor function in infants with type 1 SMA
Daily treatment with risdiplam over 24 months resulted in improved motor function and achievement of developmental motor milestones in infants with type 1 spinal muscular atrophy, according to a study published in The Lancet Neurology.
Early surgery for spinal cord injuries may accelerate motor recovery vs. delayed surgery
CHICAGO — Compared with delayed surgery, early surgery of motor-incomplete cervical spinal cord injuries may yield accelerated motor recovery 6 months after injury but similar recovery at 1 year after injury, results presented here showed.