Monoclonal Antibody

Despite being deauthorized by the FDA on Jan. 24, 2022, due to omicron variant inefficiency, two monoclonal antibody treatments were administered more than 158,000 times to patients with COVID-19, according to a study in JAMA Network Open.

WHO has recommended two monoclonal antibody treatments for Ebola virus disease.

Phenotype-directed mepolizumab therapy reduced the number of asthma exacerbations among children and adolescents with exacerbation-prone eosinophilic asthma who live in disadvantaged urban neighborhoods, researchers reported in The Lancet.

A single dose of Evusheld appears effective at preventing COVID-19 infection, without notable safety concerns, in patients at risk for infection or vaccine nonresponse, according to data published in the New England Journal of Medicine.

Patients who began taking or who switched biologics for severe asthma consistently experienced meaningfully reduced exacerbations, according to a real-world analysis published in Annals of Allergy, Asthma & Immunology.

DENVER — Monoclonal antibodies have shown promise as an emerging treatment for migraine, Stephanie J. Nahas, MD, MSEd, FAHS, FAAN, said at the American Headache Society annual scientific meeting.

The NIH launched a clinical trial to assess whether dupilumab can reduce asthma exacerbations and improve lung function and symptoms in children with poorly controlled allergic asthma in low-income urban areas.

Kidney transplant patients infected with COVID-19, including the omicron variant, benefit from neutralizing monoclonal antibody therapy, according to data published in Kidney Medicine.

When the CDC released new masking guidance at the end of February, it seemed to indicate a shift toward treating COVID-19 as something people will learn to live with.

WASHINGTON — The IV monoclonal antibody bentracimab immediately and significantly reversed the antiplatelet effect of ticagrelor in healthy older adults, with no related serious adverse events, researchers reported.