Monoclonal Antibody
VIDEO: Low risk for congestive heart failure exacerbation with Zinplava for C. difficile
CHICAGO — In this Healio video exclusive, Paul Feuerstadt, MD, FACG, AGAF, recaps results from a real-world analysis of Zinplava for prevention of recurrent Clostridioides difficile infection in patients with congestive heart failure.
Monoclonal antibody speeds time to HIV viral suppression, study finds
A monoclonal antibody was shown to speed the time to viral suppression in heavily treatment-experienced people with HIV compared with ART regimens that did not contain it, according to a study.
Monoclonal antibodies significantly reduced risk for COVID-19 hospitalization, death
Treatment with a monoclonal antibody within 2 days of a COVID-19 diagnosis reduced the risk for hospitalization or death by almost 40%, according to a study that assessed patient outcomes over a nearly 2-year period.
Eli Lilly’s novel eltrekibart shows early promise in hidradenitis suppurativa
NEW ORLEANS — A novel monoclonal antibody could be a promising treatment for hidradenitis suppurativa as phase 2 clinical trial results showed an improvement in total abscess and nodule count after 16 weeks of treatment.
First biosimilar monoclonal antibody for MS shown to be safe, effective in phase 3 trial
PB006, the first biosimilar for natalizumab, showed comparable safety, efficacy and immunogenicity to the reference monoclonal antibody therapy in patients with relapsing-remitting MS, researchers wrote in JAMA Neurology.
Tislelizumab regimen new first-line option for gastric, gastroesophageal cancer subgroup
Tislelizumab plus chemotherapy demonstrated statistically significant and clinically meaningful improvements in OS vs. chemotherapy alone among patients with PD-L1-positive, advanced gastric or gastroesophageal junction adenocarcinoma.
FDA will review monoclonal antibody for RSV protection in infants
The FDA will review a biologics license application for nirsevimab for the prevention of respiratory syncytial virus in newborns and infants, according to Sanofi and AstraZeneca, which are developing the monoclonal antibody.
Top in ID: CDC director’s COVID-19 rebound; monoclonal antibody for malaria
Last week, the CDC announced that Director Rochelle P. Walensky, MD, again tested positive for COVID-19 following a course of Paxlovid and a previous negative test.
Monoclonal antibody safely prevents malaria infection in adults
One dose of a monoclonal antibody safely protected healthy adults from malaria infection during the 6-month malaria season in Mali, according to data published in The New England Journal of Medicine and presented at a medical conference.