Monoclonal Antibody

As of Feb. 1, there have been at least 24 million illnesses, 310,000 hospitalizations and 13,000 deaths across the United States related to influenza during the 2024-2025 season, according to the CDC.

The NIH announced that it is launching a phase 2 human challenge trial of AV-1, an investigational monoclonal antibody to ease dengue virus symptoms when given before and after infection.

The next phase of pre-exposure prophylaxis against SARS-CoV-2 currently rests on the shoulders of a single monoclonal antibody product — but it may not be enough for immunocompromised populations.

The FDA has granted priority review to a Biologics License Application for nipocalimab to treat individuals with generalized myasthenia gravis who are antibody positive, according to the manufacturer.

Another monoclonal antibody for preventing respiratory syncytial virus disease in infants could enter the market as early as next year, based on the results of two studies presented at IDWeek, Merck said.

Treatment with diroximel fumarate was linked to lower rates of severe infection compared with anti-CD20 monoclonal antibodies for adults of all ages with MS, according to a poster presented at ECTRIMS.

A New York-based biotechnology company has received a $4 million grant from the NIH’s National Institute on Aging to advance a novel intranasal therapeutic to treat Alzheimer’s disease, according to a press release from the manufacturer.

Tulisokibart, an anti-TL1A monoclonal antibody, outperformed placebo in inducing clinical remission at week 12 in moderate to severe ulcerative colitis, according to a new study that also incorporated a predictive biomarker for response.

In patients with difficult-to-treat migraine, IV infusion of a novel monoclonal antibody provided superior migraine frequency relief compared with placebo in as early as 4 weeks, data show.