Monoclonal Antibody

In patients with difficult-to-treat migraine, IV infusion of a novel monoclonal antibody provided superior migraine frequency relief compared with placebo in as early as 4 weeks, data show.

The FDA has granted fast track designation for intranasal administration of a fully human anti-CD3 monoclonal antibody to treat non-active, secondary-progressive multiple sclerosis, according to the manufacturer.

In this video, Tania Jain, MBBS, director of the Immune Effector Cell Therapy Program and associate professor of oncology at Johns Hopkins University, highlights unmet needs in myeloproliferate neoplasms care and management.

Avidity Biosciences Inc. has announced positive data from the phase 1/2 FORTITUDE clinical trial of a proprietary monoclonal antibody that binds to the transferrin receptor 1 conjugated with a siRNA targeting DUX4 mRNA.

In this video, Maria Danila, MD, discusses exciting new research in the field of rheumatoid arthritis.

One subcutaneous dose of an experimental monoclonal antibody protected children from infection and clinical malaria during a 6-month malaria season in Mali, according to phase 2 results published in The New England Journal of Medicine.

Patients with active psoriatic arthritis who receive guselkumab demonstrate reduced work impairment, improved overall health and “substantial cost savings” through 2 years, according to data published in Rheumatology and Therapy.

The monoclonal antibody nirsevimab is 90% effective at preventing respiratory syncytial virus hospitalization in infants, according to research published in MMWR.

Sikander Ailawadhi, MD, discusses positioning different therapies and navigate the treatment landscape in multiple myeloma.