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Monoclonal Antibody

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October 23, 2024
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Merck’s RSV shot for infants shows promise, could be available in 2025

Merck’s RSV shot for infants shows promise, could be available in 2025

Another monoclonal antibody for preventing respiratory syncytial virus disease in infants could enter the market as early as next year, based on the results of two studies presented at IDWeek, Merck said.

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October 22, 2024
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Diroximel fumarate linked to lower rate of severe infection in MS

Diroximel fumarate linked to lower rate of severe infection in MS

Treatment with diroximel fumarate was linked to lower rates of severe infection compared with anti-CD20 monoclonal antibodies for adults of all ages with MS, according to a poster presented at ECTRIMS.

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October 03, 2024
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Tiziana Life Sciences receives $4M from NIH to advance intranasal Alzheimer’s therapy

Tiziana Life Sciences receives $4M from NIH to advance intranasal Alzheimer’s therapy

A New York-based biotechnology company has received a $4 million grant from the NIH’s National Institute on Aging to advance a novel intranasal therapeutic to treat Alzheimer’s disease, according to a press release from the manufacturer.

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September 26, 2024
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Tulisokibart bests placebo, may yield ‘important clinical benefit’ via TL1A blockade in UC

Tulisokibart bests placebo, may yield ‘important clinical benefit’ via TL1A blockade in UC

Tulisokibart, an anti-TL1A monoclonal antibody, outperformed placebo in inducing clinical remission at week 12 in moderate to severe ulcerative colitis, according to a new study that also incorporated a predictive biomarker for response.

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September 05, 2024
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Monoclonal antibody superior to placebo in reducing migraine frequency

Monoclonal antibody superior to placebo in reducing migraine frequency

In patients with difficult-to-treat migraine, IV infusion of a novel monoclonal antibody provided superior migraine frequency relief compared with placebo in as early as 4 weeks, data show.

Clinical Guidance
Immuno-Oncology
Immunotherapies

Immunotherapies

Jennifer Benbow, PhD, CCRP; Emily Baldrige, MPH; Kathryn F. Mileham, MD, FACP; Edward S. Kim, MD, MBA, FACP, FASCO

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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July 08, 2024
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FDA grants fast track designation for intranasal MS therapeutic

FDA grants fast track designation for intranasal MS therapeutic

The FDA has granted fast track designation for intranasal administration of a fully human anti-CD3 monoclonal antibody to treat non-active, secondary-progressive multiple sclerosis, according to the manufacturer.

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July 01, 2024
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VIDEO: Developing curative strategies shows unmet need in myeloproliferative neoplasms

VIDEO: Developing curative strategies shows unmet need in myeloproliferative neoplasms

In this video, Tania Jain, MBBS, director of the Immune Effector Cell Therapy Program and associate professor of oncology at Johns Hopkins University, highlights unmet needs in myeloproliferate neoplasms care and management.

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June 28, 2024
1 min read
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Monoclonal antibody for FSHD improves muscle strength with no serious adverse events

Monoclonal antibody for FSHD improves muscle strength with no serious adverse events

Avidity Biosciences Inc. has announced positive data from the phase 1/2 FORTITUDE clinical trial of a proprietary monoclonal antibody that binds to the transferrin receptor 1 conjugated with a siRNA targeting DUX4 mRNA.

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June 01, 2024
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VIDEO: New molecules, digital health applications and more drive excitement in RA research

VIDEO: New molecules, digital health applications and more drive excitement in RA research

In this video, Maria Danila, MD, discusses exciting new research in the field of rheumatoid arthritis.

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