Monash University

CHICAGO — High year-to-year cholesterol variability was linked to increased risk for cognitive decline and dementia among older adults, a speaker reported.

An AI decision support tool embedded in routine care did not meaningfully improve outcomes for patients presenting to the ED with myocardial injury, but showed signs of benefit in an all-comer cohort, a speaker reported.

Researchers estimate that semaglutide 2.4 mg is not cost-effective for secondary CVD prevention for patients with overweight or obesity without diabetes, according to an Australian study.

Older adults who sustain a hip fracture after discontinuing risedronate following at least 5 years of treatment adherence have a higher post-fracture mortality risk than those who continue using risedronate, according to study data.

A prespecified analysis of the CLEAR Outcomes trial shows that the benefits of bempedoic acid extend to patients with recurrent CV events, including a total reduction in MI risk of 31% vs. placebo.

Hospitalized smokers who received varenicline plus nicotine replacement therapy lozenges had an increased likelihood for abstinence, according to a presentation at the European Respiratory Society International Congress.

Low-dose aspirin may help lower the risk for developing diabetes among older adults, according to data that will be presented at the European Association for the Study of Diabetes annual meeting.

The first oral treatment to lower lipoprotein(a) safely lowered Lp(a) in a phase 1 study, whereas an extended phase 2 study showed durable Lp(a) lowering by an injectable treatment, researchers reported.

Hospitalization rates for psychiatric disorders vary by procedure type and psychiatric diagnosis for adults with obesity who undergo bariatric surgery, according to a study published in Obesity.

Baricitinib met the primary endpoint in one phase 3 study of patients with systemic lupus erythematosus, but failed to meet the same endpoint in a second trial aiming to repeat the results, according to data published in The Lancet.