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Minimal Residual Disease

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June 25, 2024
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VIDEO: MRD testing determines therapy cessation for patients with multiple myeloma

VIDEO: MRD testing determines therapy cessation for patients with multiple myeloma

CHICAGO — In this video, Adam Cohen, MD, spoke to Healio about the use of minimal residual disease testing to determine cessation of therapy in patients with multiple myeloma.

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April 16, 2024
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FDA panel backs residual disease as ‘reasonable surrogate’ endpoint in myeloma trials

FDA panel backs residual disease as ‘reasonable surrogate’ endpoint in myeloma trials

An FDA advisory committee unanimously voted minimal residual disease should be an accepted endpoint for accelerated approval of clinical trials investigating treatments for patients with multiple myeloma.

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March 26, 2024
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Elderly experience ‘impressive improvement’ in survival after stem cell transplant

Elderly experience ‘impressive improvement’ in survival after stem cell transplant

Among elderly patients with acute myeloid leukemia, survival outcomes for those who received an allogenic stem cell transplant have improved significantly over the past 2 decades, according to data published in Clinical Cancer Research.

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December 20, 2023
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VIDEO: Intense chemo for fit patients; venetoclax discontinuation results highlighted at ASH

VIDEO: Intense chemo for fit patients; venetoclax discontinuation results highlighted at ASH

In this video, Eunice Wang, MD discusses acute myeloid leukemia highlights from the ASH Annual Meeting and Exposition.

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December 11, 2023
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‘Unequivocal’ data emerges from trial of CLL therapy guided by measurable residual disease

‘Unequivocal’ data emerges from trial of CLL therapy guided by measurable residual disease

SAN DIEGO — A combination of targeted therapies used for a response-directed duration significantly improved outcomes compared with chemoimmunotherapy for fit patients with untreated chronic lymphocytic leukemia, according to study results.

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December 09, 2023
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Using pharmacogenomics to guide induction may reduce racial disparities in pediatric AML

Using pharmacogenomics to guide induction may reduce racial disparities in pediatric AML

Outcomes among children with acute myeloid leukemia treated with high-dose cytarabine-based regimens did not vary by race, according to study results presented at ASH Annual Meeting and Exposition.

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September 09, 2023
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Sustained MRD negativity after CAR-T improves outcomes in multiple myeloma

Sustained MRD negativity after CAR-T improves outcomes in multiple myeloma

Patients with multiple myeloma who exhibited sustained minimal residual disease negativity after treatment with ciltacabtagene autoleucel achieved longer PFS and duration of response, according to study results.

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August 17, 2023
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VIDEO: Awareness of changing landscape critical for myeloma

VIDEO: Awareness of changing landscape critical for myeloma

In this video, Nikhil Munshi, MD, Professor of Medicine at Harvard Medical School, discusses the importance of awareness for multiple myeloma and how it relates to the disease's changing treatment landscape.

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June 16, 2023
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VIDEO: Minimal residual disease data key factor in predicting leukemia relapse after CAR-T

VIDEO: Minimal residual disease data key factor in predicting leukemia relapse after CAR-T

In this video, Eunice Wang, MD, discussed a retrospective analysis looking at outcomes of chimeric antigen receptor T-cell therapy for patients diagnosed with B-cell acute lymphoblastic leukemia, presented at ASCO Annual Meeting.

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January 05, 2023
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VIDEO: Blinatumomab 'clearly positive' for minimal residual disease-negative ALL

VIDEO: Blinatumomab 'clearly positive' for minimal residual disease-negative ALL

NEW ORLEANS — In this video perspective, Richard M. Stone, MD, discusses research results on blinatumomab presented at ASH Annual Meeting and Exposition.

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