Microvascular Dysfunction

Increased intermuscular fat, not BMI, was independently associated with coronary microvascular function and major adverse CV events, according to new data published in the European Heart Journal.

Women presenting with chest pain but without signs of obstructive coronary disease may still have microvascular dysfunction, and careful imaging analyses or invasive testing can help reveal the correct diagnosis, according to a speaker.

Researchers reported that HF was independently prognostic of both cardiac and cerebral microvascular dysfunction predictive of impaired cognitive function.

Patients with psoriasis are at an increased risk for experiencing asymptomatic coronary microvascular dysfunction and should be actively evaluated for risk factors by dermatologists, according to a study.

In patients with ischemia and no obstructive coronary arteries, known as INOCA, the level of nonobstructive coronary stenosis does not affect the prognostic impact of coronary microvascular dysfunction, researchers reported.

Pretreatment evolocumab did not lower risk for periprocedural microvascular dysfunction in patients undergoing elective PCI for stable CAD who were already on statin therapy for high LDL, researchers reported.

The Coronary Vasomotor Disorders International Study Group, which is working to develop standards for diagnosing and treating coronary vasomotor disorders, held its first virtual summit on Sept. 9.

Patients with diabetes experienced significant improvement in endothelial function and microvascular reactivity while taking daily dapagliflozin, according to research presented at the virtual Heart in Diabetes Conference.

CD34+ cell therapy in patients with coronary microvascular dysfunction improved coronary flow reserve in addition to angina class and symptoms at 6 months, according to data from the ESCaPE-CMD trial.