Methylphenidate

The combined use of selective serotonin reuptake inhibitors and methylphenidate did not significantly increase adverse event risk among adults with ADHD and comorbid depression, according to a study published in JAMA Network Open.

Patients with past-month exposure to prescription amphetamines used to treat ADHD had higher odds of developing psychosis or mania compared with those without past-month exposure, according to a recent study.

About half of adults who were prescribed schedule II-controlled stimulants were concurrently exposed to other central nervous system-active drugs, many of which have withdrawal effects, complicating discontinuation, researchers reported.

Ann Childress, MD, president of the Center for Psychiatry and Behavioral Medicine Inc., discussed ADHD data from a poster presented at the American Psychiatric Nurses Association Annual Conference in a video interview with Healio.

Methylphenidate safely and effectively treated apathy in Alzheimer’s disease, according to results of a randomized placebo-controlled clinical trial published in JAMA Neurology.

Optimized dosing of delayed-release and extended-release methylphenidate increased children’s control of ADHD symptoms throughout the day, according to study results published in Journal of Clinical Psychiatry.

Methylphenidate use during pregnancy was not linked to an increased risk for malformations overall in a nationwide registry-based study with information on both prenatal and postnatal diagnoses published in Journal of Clinical Psychiatry.

ADHD affects approximately 11% of school-aged children every year, and this rate continues to rise annually. The primary treatment modality includes amphetamines and methylphenidate, with 82.5% of children being prescribed medication.

Patients with autism spectrum disorder and co-occurring ADHD can safely and effectively take medication for ADHD, according to a study conducted in the Netherlands and published in Journal of Attention Disorders.

Methylphenidate — a drug used to treat ADHD — may affect specific tracts in brain white matter in boys with the disorder, according to findings from a randomized control trial conducted in the Netherlands. The results published in Radiology suggest that the effects are age dependent.