Methotrexate

The largest dataset of U.S. patients with Behçet’s disease to date shows that nearly 80% are women, according to researchers who published their findings in Arthritis Research & Therapy.

Patients with rheumatoid arthritis who achieved greater response with tofacitinib do so regardless of whether methotrexate was added to therapy or not, according to data published in Arthritis Research & Therapy.

There is significant variation in the patterns of methotrexate use prior to initiating etanercept in patients with juvenile idiopathic arthritis, according to registry data published in Pediatric Rheumatology.

Methotrexate and azathioprine yielded similar risk-benefit ratios as first-line therapy for children with severe atopic dermatitis, according to a study.

Maximizing the disease-modifying benefits of methotrexate is one of the core principles behind the 2021 American College of Rheumatology rheumatoid arthritis guidelines.

The FDA has granted orphan drug designation to ADX-2191 for the treatment of retinitis pigmentosa, according to a press release from Aldeyra Therapeutics.

The FDA has granted orphan drug designation to ADX-2191 for the treatment of primary vitreoretinal lymphoma, according to a press release from Aldeyra Therapeutics.

Methotrexate increases the probability of remission with adalimumab or infliximab by 50% in patients with psoriatic arthritis, versus TNF-inhibitor monotherapy, according to data published in the Annals of the Rheumatic Diseases.

COVID-19-associated hospitalization was more common in patients who were taking oral methotrexate but not in those taking biologics, according to a study.

The American College of Rheumatology has released its updated treatment guidelines for rheumatoid arthritis, with a strong emphasis on the use of methotrexate before adding or switching to DMARDs, according to the lead author.