Metformin

Viona Pharmaceuticals, Inc., is voluntarily recalling 33 lots of metformin hydrochloride extended-release tablets, USP 750 mg, due to presence of N-Nitrosodimethylamine, or NDMA, according to a company statement.

In this video, Susan M. Domchek, MD, executive director of the Basser Center for BRCA and the director of the MacDonald Cancer Risk Evaluation Center at Penn Medicine, spoke with Healio about highlights from the San Antonia Breast Cancer Symposium.

Metformin did not improve outcomes for most patients with early breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.

Extended-release metformin prolonged gestation compared with placebo in women who had preterm preeclampsia, according to results of a randomized controlled trial.

Discussing weight gain and prescribing weight loss therapies or interventions for people with a BMI of 25 kg/m2 or greater could help reduce mortality risk and slow the progression of obesity, according to a speaker.

Clinicians should be cautious when prescribing certain antihyperglycemic agents for people with type 2 diabetes at risk for fracture, particularly when a patient is older with long disease duration or complications, according to a speaker.

The American Gastroenterological Association published a clinical practice update to describe the role of medications for the chemoprevention of colorectal neoplasia.

Metformin, even in low doses, may be associated with a decreased risk for basal cell carcinoma, according to a study.

In a multiethnic genome study of response to diabetes drugs, researchers identified an African-ancestry genetic variant associated with favorable insulin response to metformin, according to a speaker.

Youths diagnosed with type 2 diabetes at an older age and those who adhere to metformin therapy are more likely to progress to therapy with insulin or a non-insulin antihyperglycemic agent, according to a speaker.