Metformin

In pregnancies with type 2 diabetes, metformin plus insulin did not reduce risks for adverse neonatal outcomes compared with placebo plus insulin, according to findings presented at The Pregnancy Meeting.

Prior metformin use was associated with better survival rates among people with diabetes within 3 months of being hospitalized with pneumonia, a study published in Clinical Infectious Diseases found.

Anji Pharmaceuticals and Population Health Partners announced a strategic collaboration to accelerate the development of two clinical assets the Anji pipeline, one of which addresses kidney disease, according to the press release.

Patients with type 2 diabetes who report regular metformin use demonstrate a potential slowing of knee osteoarthritis progression, according to data published in Scientific Reports.

In a large cohort of men, pre‐diagnostic use of metformin and testosterone replacement therapy was associated with lower incidence of prostate and colorectal cancers, but not male breast cancer, according to research.

BALTIMORE — Most children with youth-onset type 2 diabetes develop macrovascular or microvascular complications within a decade of diagnosis, and the risk for beta cell function failure increases over time, according to a speaker.

NEW YORK — Patients taking lower doses of metformin may be at lower risk for age-related macular degeneration, revealing a potential novel therapy strategy, according to a speaker at the American Society of Retina Specialists meeting.

ATLANTA — Adults with type 2 diabetes who were prescribed insulin had greater risks for major osteoporotic and hip fractures than those prescribed metformin, according to study data.

In a recent study, researchers found no between-group differences in myocardial infarction, stroke or cardiovascular death among patients with prediabetes who received metformin, a lifestyle intervention or placebo.

For patients with type 2 diabetes, first-line SGLT2 inhibitors might be better than metformin when it comes to their cardiovascular health, according to results of a population-based cohort study.