Metformin

Healio spoke with David Klonoff, MD, about the latest innovations in diabetes medications.

Researchers at the American Society for Preventive Cardiology reported that the benefits of exercise occur at levels well below federal recommendations, and its impact on mortality risk is observed across ages, races and genders.

ARLINGTON, Texas — Experimental and clinical evidence suggest the diabetes drug metformin may offer CV benefits that do not depend on the presence of diabetes, and an ongoing trial will help researchers learn more, according to a speaker.

In the TRAVERSE trial, men with hypogonadism at high risk for CVD who received testosterone had a similar risk for major adverse cardiovascular events compared with those who received placebo.

Adults with overweight or obesity who received metformin shortly after a COVID-19 diagnosis had a lower risk for developing long COVID than those receiving placebo, according to study data.

Leading experts from cardiorenal metabolic specialties will present the latest research with clinical implications for diabetes, CVD and kidney disease, with a new format this year designed to drive multispecialty discussions.

Patients with type 2 diabetes who undergo metformin therapy demonstrate a 24% lower risk for osteoarthritis, compared with those who received sulfonylurea, according to data published in JAMA Network Open.

SEATTLE —SARS-CoV-2 viral loads were more than four times lower among participants in a phase 3 trial who received the diabetes drug metformin than among those who received placebo, according to findings presented at a medical conference.

Kidney transplant recipients may benefit from using metformin due to its correlation with reduced death-censored graft failure, according to data published in the American Journal of Kidney Diseases.

Children of women with type 2 diabetes who took 1,000 mg metformin twice daily during pregnancy had a similar BMI z score at age 2 years compared with those of women using placebo, according to study data.