Metformin

Leading experts from cardiorenal metabolic specialties will present the latest research with clinical implications for diabetes, CVD and kidney disease, with a new format this year designed to drive multispecialty discussions.

Patients with type 2 diabetes who undergo metformin therapy demonstrate a 24% lower risk for osteoarthritis, compared with those who received sulfonylurea, according to data published in JAMA Network Open.

SEATTLE —SARS-CoV-2 viral loads were more than four times lower among participants in a phase 3 trial who received the diabetes drug metformin than among those who received placebo, according to findings presented at a medical conference.

Kidney transplant recipients may benefit from using metformin due to its correlation with reduced death-censored graft failure, according to data published in the American Journal of Kidney Diseases.

Children of women with type 2 diabetes who took 1,000 mg metformin twice daily during pregnancy had a similar BMI z score at age 2 years compared with those of women using placebo, according to study data.

In pregnancies with type 2 diabetes, metformin plus insulin did not reduce risks for adverse neonatal outcomes compared with placebo plus insulin, according to findings presented at The Pregnancy Meeting.

Prior metformin use was associated with better survival rates among people with diabetes within 3 months of being hospitalized with pneumonia, a study published in Clinical Infectious Diseases found.

Anji Pharmaceuticals and Population Health Partners announced a strategic collaboration to accelerate the development of two clinical assets the Anji pipeline, one of which addresses kidney disease, according to the press release.

Patients with type 2 diabetes who report regular metformin use demonstrate a potential slowing of knee osteoarthritis progression, according to data published in Scientific Reports.

In a large cohort of men, pre‐diagnostic use of metformin and testosterone replacement therapy was associated with lower incidence of prostate and colorectal cancers, but not male breast cancer, according to research.