Metformin

Metformin may help adults with type 2 diabetes avoid additional cardiovascular disease events after an initial episode of acute coronary syndrome, or ACS, according to findings published in the Journal of Diabetes and its Complications.

Prediabetes was less likely to progress to type 2 diabetes among adults who took a combination of linagliptin and metformin vs. metformin alone; the combination group was also more likely to achieve normal glucose levels, according to findings published in Metabolism.

In 2019, Healio readers were interested in fertility preservation for men on testosterone therapy, the wonders of metformin, possible associations between statins and diabetes, a new osteoporosis drug and more. 

Potential carcinogenic agents may be present in metformin based on reports from non-U.S. countries, which has prompted an investigation from the FDA, according to an agency statement.

A presentation at ObesityWeek that identified multiple benefits from a low-carbohydrate diet in patients with type 2 diabetes — including weight loss, lower HbA1c, and reduced insulin resistance and cardiovascular risk — was the top story in endocrinology last week.

Insulin is needed less frequently and HbA1c is lowered more robustly when adults with type 2 diabetes do not delay combination therapy but begin treatment by taking sitagliptin and metformin together, according to findings published in Diabetic Medicine.

LAS VEGAS — When treating patients with type 2 diabetes who are attempting to lose weight, physicians must incorporate strategies that limit hypoglycemia risks, according to a speaker at ObesityWeek.

When assessing glycemic management in diabetes, measuring glycated albumin may be a more effective tool than measuring HbA1c, particularly among patients with a recent diabetes diagnosis, according to findings published in the Journal of Diabetes and its Complications.

CHICAGO — When treating patients with type 2 diabetes, physicians may have more success if they use simultaneous combination therapy immediately rather than following the traditional stepped-up method of waiting to intensify treatment, according to a speaker at the Cardiometabolic Health Congress.

CHICAGO — Intensive lifestyle interventions and metformin therapy have had significant success in treating type 2 diabetes and should both be considered when deciding on prevention and treatment, according to a presentation at the Cardiometabolic Health Congress.