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Metastatic Prostate Cancer

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February 12, 2021
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Fewer PSA screenings linked to increases in advanced prostate cancer diagnoses

Fewer PSA screenings linked to increases in advanced prostate cancer diagnoses

U.S. states with larger declines in PSA screening from 2002 to 2016 also had larger increases in incidence of metastatic prostate cancer at diagnosis, according to a presentation at Genitourinary Cancers Symposium.

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February 01, 2021
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FDA lifts clinical hold on trial of CAR-T for metastatic pancreatic, prostate cancers

FDA lifts clinical hold on trial of CAR-T for metastatic pancreatic, prostate cancers

The FDA lifted its clinical hold on a study evaluating BPX-601 and rimiducid for patients with previously treated metastatic pancreatic or prostate cancers, according to a press release from the agent’s manufacturer.

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October 07, 2020
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Rucaparib active in BRCA-mutated metastatic castration-resistant prostate cancer

Rucaparib active in <i>BRCA</i>-mutated metastatic castration-resistant prostate cancer

Rucaparib demonstrated antitumor activity among men with metastatic castration-resistant prostate cancer and a deleterious BRCA alteration, according to results of the phase 2 TRITON2 study published in Journal of Clinical Oncology.

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September 06, 2020
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Eight important updates for National Prostate Cancer Awareness Month

Eight important updates for National Prostate Cancer Awareness Month

National Prostate Cancer Awareness Month is observed every September.

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July 17, 2020
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New framework takes genetic testing guidelines for prostate cancer ‘a step further’

New framework takes genetic testing guidelines for prostate cancer &lsquo;a step further&rsquo;

All men with metastatic prostate cancer should undergo genetic testing to better inform decisions on precision medicine or clinical trial eligibility, according to recommendations developed at a multidisciplinary consensus conference.

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June 14, 2020
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AACR Academy names president-elect

AACR Academy names president-elect

Fellows of the American Association for Cancer Research Academy named Charles L. Sawyers, MD, president-elect for 2020-2021.

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May 15, 2020
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FDA approves Rubraca for prostate cancer subset

The FDA granted accelerated approval to rucaparib for treatment of men with BRCA-mutated metastatic castration resistant prostate cancer.

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April 27, 2020
6 min read
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Addition of atezolizumab to enzalutamide fails to extend OS in metastatic castration-resistant prostate cancer

Addition of atezolizumab to enzalutamide fails to extend OS in metastatic castration-resistant prostate cancer

Atezolizumab in combination with enzalutamide did not extend OS compared with enzalutamide monotherapy among men with metastatic castration-resistant prostate cancer, according to results of a randomized phase 3 IMbassador250 study presented at the virtual American Association for Cancer Research Annual Meeting.

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February 14, 2020
2 min read
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HSD3B1 genotype linked to worse outcomes in low-volume metastatic prostate cancer


  <i>HSD3B1</i> genotype linked to worse outcomes in low-volume metastatic prostate cancer

The adrenal-permissive HSD3B1 genotype appeared associated with earlier castration resistance and shorter OS among men with low-volume metastatic prostate cancer, according to results of a retrospective analysis of a randomized phase 3 study published in JAMA Oncology.

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February 12, 2020
2 min read
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Statins alone, with metformin linked to reduced mortality among men with high-risk prostate cancer

Statins alone, with metformin linked to reduced mortality among men with high-risk prostate cancer

Use of statins as monotherapy or in combination with metformin appeared associated with lower mortality among men with high-risk prostate cancer, according to results of a retrospective study published in Cancer Medicine.

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