Metastases

Isolated hepatic perfusion conferred superior overall response rates and longer PFS than best alternative care among previously untreated patients with isolated liver metastases from primary uveal melanoma according to study results.

Palliative radiation therapy for high-risk asymptomatic bone metastases significantly prolonged OS while reducing skeletal-related events compared with standard therapy, phase 2 trial results showed.

CHICAGO — Patients with bone metastases due to urothelial carcinoma had worse outcomes than those without bone metastasis, regardless of treatment or PD-L1 expression, according to a poster presentation at ASCO Annual Meeting.

Living-donor liver transplantation may be a viable option for patients with unresectable, liver-confined colorectal cancer liver metastases, according to a study published in JAMA Surgery.

BOSTON — An increase in immune checkpoint proteins was observed in metastatic melanoma patients treated with topical diphencyprone, according to a study presented at the American Academy of Dermatology Annual Meeting.

Vascular endothelial growth factor and immune checkpoint inhibitors may help prevent brain metastases among patients with solid tumors, according to results from a systematic review and meta-analysis published in Neurology.

Compared with other patients with breast cancer, those with HR–/HER2+ breast cancer have increased rates of brain metastases, according to research presented at ASCO 2021.

Patients with non-small cell lung cancer presented with brain metastases at higher rates during the COVID-19 pandemic compared with historical rates, according to prospective data presented at European Lung Cancer Virtual Congress 2021.

Acetabular reconstruction with highly porous tantalum components provided increased durability with fewer complications for patients undergoing total hip arthroplasty for periacetabular metastatic disease, according to published results.

In this video, Halle Moore, MD, director of Breast Medical Oncology in the Department of Hematology and Oncology at Cleveland Clinic Taussig Cancer Institute, spoke with Healio about presentations in breast cancer at the virtual ASCO Annual Meeting.