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Metabolic Dysfunction-Associated Steatotic Liver Disease

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November 13, 2023
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MASH resolution without worsening fibrosis boosts 15-year survival after bariatric surgery

MASH resolution without worsening fibrosis boosts 15-year survival after bariatric surgery

BOSTON — Resolution of metabolic dysfunction-associated steatohepatitis without worsening of fibrosis was linked to long-term survival after bariatric surgery, similar to that of patients without baseline MASH, according to a presenter.

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November 12, 2023
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Weight loss program led by advanced practice providers outperforms routine care in MASLD

Weight loss program led by advanced practice providers outperforms routine care in MASLD

BOSTON — An intensive, advanced practice provider-guided weight loss program helped patients with metabolic dysfunction-associated steatotic liver disease achieve statistically significant weight loss vs. standard of care.

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November 12, 2023
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Q&A: FAST score, other noninvasive tests help identify, stratify at-risk MASH patients

Q&A: FAST score, other noninvasive tests help identify, stratify at-risk MASH patients

BOSTON — Researchers recommended the FibroScan-aspartate aminotransferase score as a noninvasive biomarker to stratify patients at risk for metabolic dysfunction-associated steatohepatitis, when used with different cutoff points for HbA1C.

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November 11, 2023
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Model predicts a 23% increase in MASLD prevalence from 2020 to 2050

Model predicts a 23% increase in MASLD prevalence from 2020 to 2050

BOSTON — A new model forecasted a “substantial clinical burden” of metabolic dysfunction-associated steatotic liver disease in the next 30 years, including twice as many cases of liver cancer and triple the need for liver transplantation.

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November 11, 2023
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Food insecurity, low household income raises risk for MASLD in adolescents

Food insecurity, low household income raises risk for MASLD in adolescents

BOSTON — Food insecurity in adolescents is “very tightly associated” with metabolic dysfunction-associated steatotic liver disease, which may result from not being able to eat or purchase a balanced meal, according to a researcher.

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November 03, 2023
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Obesity odds more than twice as high for women than men in low- and middle-income nations

Obesity odds more than twice as high for women than men in low- and middle-income nations

Women living in low- and middle-income countries have a higher prevalence of obesity and other cardiometabolic disorders than men, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

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October 30, 2023
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Testosterone replacement does not improve steatotic liver disease for older men

Testosterone replacement does not improve steatotic liver disease for older men

Twelve months of testosterone replacement therapy did not improve metabolic dysfunction-associated steatotic liver disease in a group of older men with hypogonadism, according to a secondary analysis of the T Trials.

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October 28, 2023
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Shift from NAFLD to MASLD does not necessarily require change in management

Shift from NAFLD to MASLD does not necessarily require change in management

VANCOUVER, British Columbia — Despite recent changes in nomenclature for metabolic dysfunction-associated steatotic liver disease, an expert here noted that clinical pathways largely remain the same and require reinforcing.

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October 24, 2023
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‘Often overlooked’: Insulin resistance tops risk predictors for MASLD in lean patients

‘Often overlooked’: Insulin resistance tops risk predictors for MASLD in lean patients

VANCOUVER, British Columbia — Insulin resistance, HbA1c and waist circumference represent independent risk factors for metabolic dysfunction-associated steatotic liver disease among lean patients, according to data presented here.

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