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Metabolic Dysfunction-Associated Liver Disease

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December 30, 2024
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Hot-button issues: Experts share opinions on shifts in clinical innovation, policy in 2024

Hot-button issues: Experts share opinions on shifts in clinical innovation, policy in 2024

Throughout 2024, experts in the fields of gastroenterology and hepatology weighed in on cutting edge research, emerging trends and policies, as well as clinical innovations shaping the future of patient care.

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November 18, 2024
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Novel farnesoid X receptor agonist safe, reduces liver fat content by up to 22.8% in MASH

Novel farnesoid X receptor agonist safe, reduces liver fat content by up to 22.8% in MASH

SAN DIEGO — Once-daily FXR314 was well-tolerated and safely improved liver fat content and biochemical markers over 16 weeks in patients with metabolic dysfunction-associated steatohepatitis, according to research at The Liver Meeting.

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June 08, 2024
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‘Unprecedented level of fibrosis improvement’ through 96 weeks with efruxifermin for MASH

‘Unprecedented level of fibrosis improvement’ through 96 weeks with efruxifermin for MASH

Treatment with efruxifermin resulted in significant improvement in fibrosis at week 24 in patients with metabolic dysfunction-associated steatohepatitis, which was “sustained and expanded through week 96,” according to late-breaking data.

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May 22, 2024
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Prevalence of advanced fibrosis similar in lean, non-lean MASLD, linked to genetic risk

Prevalence of advanced fibrosis similar in lean, non-lean MASLD, linked to genetic risk

WASHINGTON — The risk for advanced fibrosis was similar among patients with lean and non-lean metabolic dysfunction-associated steatotic liver disease and may be associated with genetic risk, according to data at Digestive Disease Week.

CME
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The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis

The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis
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News
November 28, 2023
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Aldafermin 3 mg significantly reduced Enhanced Liver Fibrosis score in MASH

Aldafermin 3 mg significantly reduced Enhanced Liver Fibrosis score in MASH

BOSTON — Treatment with aldafermin 3 mg appeared to be well-tolerated and significantly reduced Enhance Liver Fibrosis score after 48 weeks among patients with metabolic dysfunction-associated steatohepatitis, according to a presenter.

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November 15, 2023
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VIDEO: TERN-501 ‘could be a best-in-class molecule’ alone, as combination therapy for MASH

VIDEO: TERN-501 ‘could be a best-in-class molecule’ alone, as combination therapy for MASH

BOSTON — Treatment with TERN-501, a selective thyroid hormone receptor beta agonist, reduced liver fat content and fibro-inflammation among patients with presumed metabolic dysfunction-associated steatohepatitis, late-breaking data showed.