Mcmaster University

Tranexamic acid vs. placebo for life-threatening, major and critical organ bleeding in patients undergoing noncardiac surgery.

Influenza vaccine or placebo in patients with HF.

SAN FRANCISCO — Awake prone positioning did not reduce endotracheal intubation at 30 days compared with usual care in patients with acute hypoxemic respiratory failure from COVID-19, according to results of the COVI-PRONE trial.

Among patients who received implantable cardioverter defibrillator therapy, a subcutaneous vs. transvenous approach reduced major lead-related complications by 92% with no loss in device performance, according to data from the ATLAS trial.

Lipoprotein(a) may have a causal role in incident atrial fibrillation risk, independent of its effect on atherosclerotic CVD, according to an analysis of U.K. Biobank data.

WASHINGTON — People with HF who received an annual influenza vaccine had a reduction in major CV events during peak influenza season and lower rates of hospitalization and pneumonia on a year-round basis, according to the IVVE study.

WASHINGTON — Complete revascularization, as opposed to culprit lesion-only revascularization, was associated with better angina-related quality of life in patients with STEMI and multivessel CAD, a speaker reported.

WASHINGTON — Tranexamic acid administered intravenously before and after noncardiac surgery lowered the risk for life-threatening, major and critical organ bleeding compared with placebo, according to results of the POISE-3 trial.

For prevention of venous thromboembolism after noncardiac surgery, direct oral anticoagulants may be preferred over low-molecular-weight heparin, according to a systematic review and meta-analysis.

Patients with venous thromboembolism and obesity had a lower mortality risk than those with normal BMI, according to a study published in Journal of Thrombosis and Haemostasis.