Mcmaster University

Gefapixant only showed small effects vs. placebo on objective cough frequency, cough severity and quality of life among adults with refractory or unexplained chronic cough, according to results of a systematic review and meta-analysis.

Colchicine did not reduce risk for perioperative atrial fibrillation or myocardial injury vs. placebo after noncardiac chest surgery, but a speaker noted a slight trend toward protection from a composite of both outcomes.

Researchers reported that a diet comprised of higher amounts of fruit, vegetables, nuts, legumes, fish and whole-fat dairy is associated with lower CVD and mortality in all world regions, especially in countries with lower income.

Prophylactic concizumab conferred significant reductions in treated spontaneous and traumatic bleeds among patients with hemophilia A or B without inhibitors, a primary analysis of the randomized phase 3 explorer8 study showed.

As a seemingly ever-increasing body of data support physical activity in patients with osteoarthritis, a growing discussion is addressing the distinction between pain and harm, and how the two are experienced by those with the disease.

AstraZeneca announced the ANNEXA phase IV trial assessing the safety and efficacy of andexanet alfa stopped early after achieving prespecified criteria on hemostatic efficacy vs. usual care, according to a press release.

In patients with an implantable cardioverter defibrillator, those who had transvenous leads had worse outcomes related to tricuspid regurgitation than those who had subcutaneous leads, according to new data from the ATLAS trial.

After adjusting for factors including use of long-term therapies, the risk for mortality within 30 days of first heart failure hospitalization was between three- and fivefold higher in lower-income vs. higher-income countries, data show.

Early treatment with oral fluvoxamine plus inhaled budesonide reduced the incidence of progression to severe disease among high-risk outpatients with COVID-19, according to research published in Annals of Internal Medicine.

The prevalence of diabetic retinopathy among children and adolescents with type 2 diabetes greatly increases 5 years after diabetes diagnosis, according to findings from a systematic review and meta-analysis.