Massachusetts General Hospital

CHICAGO — Olaparib monotherapy significantly improved overall response rates and PFS, with no new safety signals, compared with nonplatinum chemotherapy among women with germline BRCA-mutated, platinum-sensitive relapsed ovarian cancer, according to results of the randomized phase 3 SOLO3 study presented at ASCO Annual Meeting.

CHICAGO — BLU-667 induced durable antitumor responses with manageable toxicity among patients with advanced RET fusion-positive non-small cell lung cancer, according to updated results of the ongoing ARROW study presented at ASCO Annual Meeting.

CHICAGO — The Conquer Cancer Foundation of ASCO presented ASCO Annual Meeting Merit Awards to more than 100 oncology professionals.

CHICAGO — Racial and ethnic disparities in time to breast biopsy disappeared after implementation of a same-day biopsy program, according to a study presented at ASCO Annual Meeting. Brian N. Dontchos, MD, diagnostic radiology specialist at Massachusetts General Hospital and faculty advisor to the study, told HemOnc Today. “Given our findings, we believe that a similar impact on disparities could be seen by implementing same-day care models in other subspecialties.”

SAN FRANCISCO — Among patients with chemotherapy-induced cardiomyopathy eligible for cardiac resynchronization therapy, CRT improved left ventricular function and promoted reverse remodeling, according to the MADIT-CHIC study.

SAN FRANCISCO — In patients with HF with reduced ejection fraction, long-term use of a cardiac resynchronization therapy defibrillator was associated with better outcomes than use of an implantable cardioverter defibrillator alone, according to the results of the After RAFT study.

SAN FRANCISCO — A subcutaneous implantable cardioverter defibrillator was safe and effective in a higher-risk population than had been evaluated in previous trials, according to results of the UNTOUCHED study.

A chimeric antigen receptor T-cell therapy targeting B-cell maturation antigen produced high response rates with manageable toxicity among patients with heavily pretreated relapsed or refractory multiple myeloma, according to results of a phase 1 study published in The New England Journal of Medicine.

Screening with 3-D digital breast tomosynthesis appeared associated with increases in both specificity and proportion of breast cancers detected with better prognosis than two-dimensional digital mammography, according to results of a retrospective observational study published in JAMA Oncology.

VIENNA — A new, open-access simulator gives providers the tools to show natural progression of non-alcoholic fatty liver disease to their patients using personalized factors, according to an expert at the International Liver Congress.