Massachusetts General Hospital
STEP data: Semaglutide promises ‘new era’ in medical therapy for obesity
Superior weight-loss efficacy with the GLP-1 receptor agonist semaglutide demonstrated in the phase 3 STEP studies suggests clinicians have a new opportunity to control obesity and its medical complications, including type 2 diabetes.
Organizations launch program to improve AF management in underserved areas
The American College of Cardiology, the Heart Rhythm Society and the Bristol Myers Squibb/Pfizer alliance announced they have launched a program to improve management of atrial fibrillation in underserved communities.
Neoadjuvant talazoparib induces pathologic complete response in breast cancer subset
Neoadjuvant talazoparib conferred pathologic complete response rates comparable with those of anthracycline- and taxane-based chemotherapy regimens among patients with germline BRCA1/BRCA2-mutated, HER2-negative early breast cancer.
Refractory Lyme arthritis may be driven by 'maladaptive immune response'
A maladaptive immune response may be prompting arthritic complications in patients with persistent and drug-refractory Lyme disease, according to a speaker at the EULAR 2021 Congress.
Genetics play role in how DASH diet impacts gout risk among women
Although the DASH diet can lower gout risk in women regardless of genetics, nonadherence can result in a greater risk in those with a higher predisposition for elevated serum urate, according to a speaker at the EULAR 2021 Congress.
Major depressive episodes after COVID-19 illness differ from typical presentation
Apparent major depressive episodes after COVID-19 illness appeared distinct from those usually observed among adults, according to results of a survey study in a research letter published in JAMA Network Open.
More than 20% of stable outpatients with CAD experience monthly angina
Among stable outpatients with CAD, 21.2% reported experiencing angina at least once monthly, researchers reported.
CAR-T with synthetic binder shows ‘very promising’ results in advanced multiple myeloma
A novel chimeric antigen receptor T-cell therapy induced responses in the first 12 evaluable patients with relapsed or refractory multiple myeloma treated in a phase 1 dose-escalation trial.
Immediate-read mammography program reduces disparities, ‘eliminates a huge barrier’
The problem of racial disparities in cancer care is multifaceted, and clinicians or institutions seeking to address the issue may not know where to begin.
Screening endoscopy after age 75 years lowers risk for colorectal cancer incidence, death
Screening endoscopy among otherwise healthy individuals aged older than 75 years appeared to lower the risk for colorectal cancer incidence and cancer-associated mortality, according to study results published in JAMA Oncology.