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Massachusetts General Hospital

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December 15, 2021
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Geography, race/ethnicity impact late-life depression severity

Geography, race/ethnicity impact late-life depression severity

Severity in symptoms of late-life depression may be linked to geography, as well as racial/ethnic disparities depending on location, according to a cohort study published in The American Journal of Geriatric Psychiatry.

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December 15, 2021
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Obesity plus genetic predisposition exacerbates risk for gout in women

Obesity plus genetic predisposition exacerbates risk for gout in women

Although excess adiposity and genetic predisposition are individually strongly linked to greater gout risk, both combined result in a higher risk than the sum of each, especially in women, according to data.

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December 11, 2021
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Conversations about goals of care often occur too late in high-risk AML

Conversations about goals of care often occur too late in high-risk AML

Goals-of-care discussions often occur too late for patients with poor-prognosis, high-risk acute myeloid leukemia, according to study results presented at ASH Annual Meeting and Exposition.

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December 10, 2021
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First wave of COVID-19 in Canada magnified incidence of anorexia nervosa

First wave of COVID-19 in Canada magnified incidence of anorexia nervosa

The initial surge of the COVID-19 pandemic uncovered a rise in diagnoses of and hospitalizations for anorexia nervosa in both children and adolescents, per a cross-sectional study from Canada published in JAMA Network Open Pediatrics.

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December 09, 2021
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Most patients with COVID-19-linked disorders of consciousness recover

Most patients with COVID-19-linked disorders of consciousness recover

Patients with COVID-19-associated disorders of consciousness who survived the infection were highly likely to regain consciousness, according to results of a prospective, multimodal study.

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December 07, 2021
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Tocilizumab delays flare, reduces glucocorticoid dose in new-onset giant cell arteritis

Tocilizumab delays flare, reduces glucocorticoid dose in new-onset giant cell arteritis

Weekly tocilizumab delays initial flare and reduces glucocorticoid exposure in patients with relapsing and new-onset giant cell arteritis, according to data published in Rheumatology.

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December 07, 2021
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Elacestrant extends PFS among certain women with metastatic breast cancer

Elacestrant extends PFS among certain women with metastatic breast cancer

Elacestrant improved outcomes compared with standard endocrine therapy for certain women with pretreated ER-positive, HER2-negative metastatic breast cancer, according to results presented at San Antonio Breast Cancer Symposium.

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December 02, 2021
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Racial, ethnic minority populations underrepresented in precision oncology studies

Racial, ethnic minority populations underrepresented in precision oncology studies

Racial and ethnic minority populations remain underrepresented in many precision oncology trials relative to their cancer incidence in the U.S., according to study results published in JAMA Network Open.

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November 30, 2021
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Social media use tied to worse depression symptoms in adults

Social media use tied to worse depression symptoms in adults

Social media use may increase depressive symptoms among adults, according to results of a survey study published in JAMA Network Open.

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November 18, 2021
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Higher dosing, duration of use intensifies risk for hydroxychloroquine retinopathy

Higher dosing, duration of use intensifies risk for hydroxychloroquine retinopathy

The risk for hydroxychloroquine retinopathy increases with higher dosing per actual and ideal body weight, and with longer duration of use, according to data presented at ACR Convergence 2021.

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