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Massachusetts General Hospital

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June 23, 2022
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Growth hormone reduces liver fat, inflammation in adults with NAFLD

Growth hormone reduces liver fat, inflammation in adults with NAFLD

ATLANTA — Adults with overweight or obesity and nonalcoholic fatty liver disease, or NAFLD, had a significant reduction in liver fat and inflammation with daily subcutaneous growth hormone administration, according to a speaker.

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June 15, 2022
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Uncertainty leads to depression, anxiety in patients with systemic autoimmune diseases

Uncertainty leads to depression, anxiety in patients with systemic autoimmune diseases

Patients with systemic autoimmune rheumatic disorders who show evidence of illness-related uncertainty also tend to experience depression, anxiety and increased sickness impact, according to data published in the Journal of Rheumatology.

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June 11, 2022
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Lower tibial cortical BMD, bone strength observed in male runners vs. nonathletes

Lower tibial cortical BMD, bone strength observed in male runners vs. nonathletes

ATLANTA — Male runners are more likely to have lower tibial bone mineral density and strength compared with nonathletes, according to a presenter at ENDO 2022.

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June 09, 2022
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Sequential pembrolizumab may be optimal timing with chemoradiotherapy in head/neck cancer

Sequential pembrolizumab may be optimal timing with chemoradiotherapy in head/neck cancer

CHICAGO — A sequential schedule of fixed-dose pembrolizumab with chemoradiotherapy conferred numerically higher PFS rates vs. concurrent timing of the drug among patients with locally advanced head and neck cancer, study results showed.

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June 08, 2022
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Adjuvant chemotherapy plus endocrine therapy fails to increase OS in breast cancer subset

Adjuvant chemotherapy plus endocrine therapy fails to increase OS in breast cancer subset

CHICAGO — The addition of chemotherapy to endocrine therapy did not extend OS after surgery among older patients with ER-positive, HER2-negative breast cancer with a high tumor genomic grade index.

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June 07, 2022
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Acetaminophen may reduce immunotherapy efficacy in patients with cancer

Acetaminophen may reduce immunotherapy efficacy in patients with cancer

CHICAGO — Acetaminophen suppressed antitumor immunity in a cohort of patients with cancer, according to study results presented during ASCO Annual Meeting.

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June 07, 2022
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First patient gains insulin independence with novel stem cell-derived islet cell therapy

First patient gains insulin independence with novel stem cell-derived islet cell therapy

NEW ORLEANS — A man with long-standing type 1 diabetes and no endogenous insulin production achieved insulin independence after an infusion of an investigational stem cell-derived pancreatic islet cell therapy, researchers reported.

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June 05, 2022
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Investigational CAR-T shows promise for advanced multiple myeloma

Investigational CAR-T shows promise for advanced multiple myeloma

CHICAGO — A single dose of a novel chimeric antigen receptor T-cell therapy induced objective response among all treated patients with relapsed or refractory multiple myeloma, according to study results presented at ASCO Annual Meeting.

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May 25, 2022
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Polygenic component associated with HCM risk, offering prediction tool

Polygenic component associated with HCM risk, offering prediction tool

Rare and common genetic variants contribute substantially to susceptibility to hypertrophic cardiomyopathy in the general population and can help improve risk prediction beyond clinical factors, researchers reported.

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May 23, 2022
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Genetic risk, low diet quality increase type 2 diabetes risk

Genetic risk, low diet quality increase type 2 diabetes risk

Genetic risk and poorer diet quality each independently increase the risk for developing type 2 diabetes, according to study data.

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