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Major Depressive Disorder

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January 22, 2025
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FDA approves Spravato as monotherapy for adults with major depressive disorder

FDA approves Spravato as monotherapy for adults with major depressive disorder

The FDA has approved a supplemental new drug application for Spravato, an esketamine nasal spray that can be used as monotherapy for adults with treatment-resistant depression, Johnson & Johnson announced in a press release.

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January 21, 2025
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Protein-binding biomarker may indicate stress-related increase in suicidal ideation

Protein-binding biomarker may indicate stress-related increase in suicidal ideation

Presence of a protein-binding biomarker in a small cohort of adults with depression may be an indicator that suicidal ideation increases because of elevated stress, according to research from JAMA Psychiatry.

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December 30, 2024
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Dementia risk factors, new depression therapy: Here are the top psych stories of 2024

Dementia risk factors, new depression therapy: Here are the top psych stories of 2024

At the Alzheimer's Association International Conference, the Lancet Commission unveiled two new modifiable risk factors for dementia: high cholesterol and vision loss.

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November 07, 2024
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White matter alterations in brain strongly associated with cognitive impairment

White matter alterations in brain strongly associated with cognitive impairment

Alterations in white matter integrity were linked to cognitive impairment, and associations were strongest in those with major depressive disorder compared with healthy controls, according to new research.

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September 05, 2024
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High-dose psilocybin may help treat depressive symptoms, with small effect size

High-dose psilocybin may help treat depressive symptoms, with small effect size

High-dose psilocybin showed the potential to treat depressive symptoms, although the effect size appeared small and comparable to that of escitalopram, according to results of a network meta-analysis published in The BMJ.

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August 01, 2024
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Dermatologists play significant role in detecting, addressing body dysmorphic disorder

Dermatologists play significant role in detecting, addressing body dysmorphic disorder

In a new study published in the Journal of Drugs in Dermatology, researchers discussed how and why dermatologists have a significant role to play in the diagnosing and addressing of body dysmorphic disorder.

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July 23, 2024
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VIDEO: ‘New hope on the horizon’ in psychedelic medicine

VIDEO: ‘New hope on the horizon’ in psychedelic medicine

NEW YORK — In this Healio Video Perspective, Reid Robison, MD, MBA, senior principal investigator at Numinus, a company that conducts clinical trials in psychedelics, discusses promising new treatment options for psychiatric conditions.

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July 22, 2024
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J&J seeks FDA approval of esketamine as monotherapy for treatment-resistant depression

J&J seeks FDA approval of esketamine as monotherapy for treatment-resistant depression

Johnson & Johnson announced that it has submitted a supplemental new drug application for the approval of esketamine nasal spray as a monotherapy for adults with treatment-resistant depression.

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June 10, 2024
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FDA grants expanded indication for Deep TMS for treatment of depression in older adults

FDA grants expanded indication for Deep TMS for treatment of depression in older adults

The FDA has granted an expanded indication for BrainsWay’s Deep Transcranial Magnetic Stimulation system for depression treatment in patients aged 22 to 86 years, according to a company press release.

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May 10, 2024
6 min read
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'A wild west': Patients seek new depression treatments with different mechanisms of action

'A wild west': Patients seek new depression treatments with different mechanisms of action

Patients have become increasingly disillusioned with traditional depression treatments, and the search for new therapies has created some chaos in the field, according to experts.

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