Maintenance

A newly developed malnutrition-inflammation complex syndrome score revealed an association between a high score and increased risks of bone-cardiovascular axis disorders in patients receiving maintenance hemodialysis.

In this video, Healio spoke with Farhad Ravandi, MD, about the promise of maintenance therapy in AML, which was discussed at the Society of Hematologic Oncology Annual Meeting.

Remo Panaccione, MD, of the University of Calgary, reported Rinvoq safely and effectively maintained moderate-to-severe ulcerative colitis.

Zeposia compared with placebo was more effective as an induction and maintenance therapy in patients with moderately to severely active ulcerative colitis, according to a study published in The New England Journal of Medicine.

Maintenance therapy with 5-fluoruracil/leucovorin plus panitumumab better maintained wildtype metastatic colorectal cancer than 5-fluoruracil/leucovorin alone, according to data from a study presented at ASCO21.

Overall survival of patients with metastatic colorectal cancer who completed 16 weeks of first-line chemotherapy treatment was unaffected by oral maintenance of capecitabine compared with no treatment, according to data from phase 3 trial presented at ASCO21.

COVID-19 infections in patients with hematologic malignancies tend to have a much worse prognosis, with mortality rates twice as high as those of patients without hematologic malignancies. These rates are currently up to 34% overall among adults and up to 47% among those aged older than 60 years. Underlying immunosuppression related to the malignancy itself and further potentiated by the therapy likely contributes to high mortality seen among these patients.

Citalopram combined with standard mood stabilizers did not offer clinically meaningful benefit vs. placebo for acute or maintenance treatment of bipolar depression, according to study results published in Journal of Clinical Psychiatry.

Methadone maintenance dispensed via pharmacy vs. opioid treatment programs may reduce driving times to receive this treatment in the U.S., according to results of a descriptive cross-sectional study published in JAMA Psychiatry.

In this video, Ya-Chi Ho, MD, MS, PhD, instructor of medicine at the Johns Hopkins University School of Medicine and co-leader of the HIV Cure Scientific Working Group at the Johns Hopkins Center for AIDS Research, reviews the approaches to HIV cure that were discussed at ASM Microbe 2016.