Lynch Syndrome

Endometrial cancer has become the number one cancer diagnosis among U.S. women, particularly among the younger population, with nearly 68,000 cases and 14,000 deaths expected annually, according to Robert Wenham, MD.

VANCOUVER, British Columbia — A digital risk assessment tool and genetic testing program can be helpful in identifying patients with high-risk cancer susceptibility syndromes, according to a presenter at the ACG Annual Scientific Meeting.

Population genomic screening for Lynch syndrome, familial hypercholesterolemia and hereditary breast and ovarian cancer may be cost-effective for adults aged younger than 40 years if the cost is “relatively low,” researchers reported.

Individuals with Lynch syndrome who took resistant starch supplements for at least 2 years developed significantly fewer non-colorectal cancers, results of a 10-year follow-up study in Cancer Prevention Research showed.

Complete immunohistochemistry diagnostics reduced the need for subsequent gene testing in patients with Lynch syndrome, according to research published in Clinical Gastroenterology and Hepatology.

GI OnDEMAND has recently partnered with Ambry Genetics to integrate online genetic counseling and testing services into gastroenterology practices in the United States to better identify hereditary gastrointestinal cancer syndromes.

A steep increase in incidence of colorectal cancer among patients aged between 49 and 50 years may suggest that many cases go undetected in younger patients before they reach routine, average-risk screening at age 50 years, according to data published in JAMA Network Open.

Endoscopic surveillance for Lynch syndrome using high-definition white-light endoscopy was noninferior to surveillance using pancolonic chromoendoscopy, according to study results.

  Healio spoke to Kevin M. Elias, MD, director of the Gynecologic Oncology Laboratory at Brigham and Women's Hospital and assistant professor of obstetrics, gynecology and reproductive biology at Harvard Medical School, about screening for endometrial cancer.

  Healio spoke to Kevin M. Elias, MD, director of the Gynecologic Oncology Laboratory at Brigham and Women's Hospital and assistant professor of obstetrics, gynecology and reproductive biology at Harvard Medical School, about screening for endometrial cancer.