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Lymphoma

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June 07, 2021
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Copanlisib regimen improves outcomes in pretreated follicular, marginal zone lymphoma

Copanlisib regimen improves outcomes in pretreated follicular, marginal zone lymphoma

The addition of copanlisib to rituximab extended PFS among patients with relapsed follicular lymphoma or marginal zone lymphoma, according to a subset analysis of the randomized phase 3 CHRONOS-3 trial.

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June 04, 2021
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Inpatient hospitalization, mortality high among patients with cancer, COVID-19

Inpatient hospitalization, mortality high among patients with cancer, COVID-19

Patients with cancer who contracted COVID-19 had high risk for inpatient hospital admission and death, according to study results presented during the virtual ASCO Annual Meeting.

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May 19, 2021
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FDA grants priority review to Brukinsa for pretreated marginal zone lymphoma

FDA grants priority review to Brukinsa for pretreated marginal zone lymphoma

The FDA granted priority review designation to zanubrutinib for treatment of certain adults with marginal zone lymphoma, according to the agent’s manufacturer.

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May 13, 2021
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Brentuximab vedotin shows promise in high-risk pediatric Hodgkin lymphoma

Brentuximab vedotin shows promise in high-risk pediatric Hodgkin lymphoma

The replacement of vincristine with brentuximab vedotin in standard front-line treatment appeared safe and effective among children and adolescents with high-risk classical Hodgkin lymphoma, according to phase 2 study results.

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May 12, 2021
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FDA clears IND application for CD20-directed CAR-T to treat B-cell malignancies

FDA clears IND application for CD20-directed CAR-T to treat B-cell malignancies

The FDA cleared an investigational new drug application for MB-106, a chimeric antigen receptor T-cell therapy designed to treat patients with relapsed or refractory, CD20-positive B-cell malignancies.

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May 04, 2021
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Access to CAR T-cell therapy faces regional challenges

Access to CAR T-cell therapy faces regional challenges

The additional distance that Americans must travel to receive chimeric antigen receptor T-cell therapy compared with other cancer treatments varies greatly by region, according to a study by health care consulting firm Avalere Health.

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May 03, 2021
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FDA clears IND application for CAR-natural killer cell therapy to treat B-cell malignancies

FDA clears IND application for CAR-natural killer cell therapy to treat B-cell malignancies

The FDA cleared an investigational new drug application for NKX019, a chimeric antigen receptor-natural killer cell therapy for patients with relapsed or refractory B-cell malignancies, according to the agent’s manufacturer.

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April 27, 2021
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The case for CAR T cells as earlier treatment requires more evidence

The case for CAR T cells as earlier treatment requires more evidence

The development of chimeric antigen receptor T cells has provided hope for patients with hematologic malignancies, but their commercial use has been limited to an option of last resort.

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April 26, 2021
5 min read
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American Association for Cancer Research forum addresses COVID-19 vaccine hesitancy

American Association for Cancer Research forum addresses COVID-19 vaccine hesitancy

The medical research community’s swift response to the COVID-19 pandemic has led to the development of multiple vaccines within less than a year and the full vaccination of 94 million Americans against the novel coronavirus.

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April 26, 2021
2 min read
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Leukemia & Lymphoma Society investments support immunotherapy for blood cancers

Leukemia & Lymphoma Society investments support immunotherapy for blood cancers

The Leukemia & Lymphoma Society’s therapy acceleration program announced five investments intended to hasten development of immunotherapies to treat blood cancers.

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