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Lymphoma

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April 26, 2022
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CAR-T effective, safe for certain patients with central nervous system-involved lymphoma

SALT LAKE CITY — Chimeric antigen receptor T-cell therapy appeared effective for patients with primary or secondary central nervous system large B-cell lymphoma, according to study results.

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April 26, 2022
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Dual-targeting ‘the next step’ for CAR T-cell therapy in advanced non-Hodgkin lymphoma

A bispecific chimeric antigen receptor T-cell therapy continues to show promising efficacy for patients with relapsed or refractory B-cell non-Hodgkin lymphoma, results of a phase 1/phase 2 trial suggest.

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April 25, 2022
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Allogeneic HSCT induces durable response in B-cell lymphoma

SALT LAKE CITY — Patients with relapsed or refractory large B-cell lymphoma who failed chimeric antigen receptor T-cell therapy achieved durable responses with allogeneic hematopoietic stem cell transplantation, according to study results.

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April 22, 2022
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FDA grants fast track designation to gamma-delta T-cell therapy for advanced lymphoma

The FDA granted fast track designation to ADI-001 for the treatment of relapsed or refractory B-cell non-Hodgkin lymphoma.

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April 22, 2022
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FDA panel: PI3K inhibitor approvals for blood cancers should be backed by randomized data

The FDA Oncologic Drugs Advisory Committee voted Thursday in favor of randomized data to support future approvals of phosphatidylinositol-3-kinase inhibitors, which are being developed for patients with hematologic malignancies.

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April 21, 2022
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Top in hem/onc: COVID-19 vaccine in people with cancer; advanced lymphoma treatment

An investigational COVID-19 vaccine elicited immune responses in patients with B-cell deficiencies, including those with lymphoma and leukemia, according to recent data.

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April 19, 2022
11 min read
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COVID-19 prevention must extend beyond vaccines for patients receiving cell therapies

Infection mitigation with vaccines is essential for patients with hematologic malignancies because they are at increased risk for severe infection, hospitalization and mortality if they contract COVID-19.

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April 18, 2022
5 min read
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Older woman referred for unilateral eye redness

An 81-year-old retired teacher presented to the cornea clinic for right eye redness and irritation that started 2 months prior.

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April 15, 2022
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Supported by fellowship, oncologist leads trial of older patients with lymphoma

Elizabeth Brém, MD, was named a Coltman Fellow to support her work on SWOG’s S1918 trial, designed to assess a reduced-dose chemotherapy regimen in patients aged 75 years or older with newly diagnosed aggressive non-Hodgkin lymphoma.

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April 14, 2022
7 min read
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From referral to infusion: Accelerating the CAR-T process

There are many frustrating aspects to a cancer diagnosis.

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