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Lymphoma

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June 21, 2022
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Risk for maternal death higher in pregnancies complicated due to cancer

Risk for maternal death higher in pregnancies complicated due to cancer

Risks for severe maternal morbidity and mortality appeared higher among pregnancies complicated by cancer, according to study results in a research letter published in JAMA Oncology.

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June 14, 2022
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Bortezomib extends survival of children with newly diagnosed T-cell lymphoblastic lymphoma

Bortezomib extends survival of children with newly diagnosed T-cell lymphoblastic lymphoma

The addition of bortezomib to chemotherapy significantly improved survival outcomes among children and young adults with T-cell lymphoblastic lymphoma, according to phase 3 study results published in Journal of Clinical Oncology.

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June 12, 2022
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Intramuscular recombinant Erwinia asparaginase active, safe in leukemia, lymphoma subsets

Intramuscular recombinant <i>Erwinia</i> asparaginase active, safe in leukemia, lymphoma subsets

A phase 2/phase 3 study assessed intramuscular asparaginase Erwinia chrysanthemi (recombinant)-rywn for patients with acute lymphoblastic leukemia or lymphoblastic lymphoma who developed hypersensitivity to E. coli-derived L-asparaginase.

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June 10, 2022
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FDA grants RMAT designation to ALLO-501 CAR-T for advanced large B-cell lymphoma

FDA grants RMAT designation to ALLO-501 CAR-T for advanced large B-cell lymphoma

The FDA granted regenerative medicine advanced therapy designation to ALLO-501, a chimeric antigen receptor T-cell therapy, for the treatment of adults with relapsed or refractory large B-cell lymphoma.

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June 09, 2022
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Brentuximab regimen effective for younger patients with advanced-stage Hodgkin lymphoma

Brentuximab regimen effective for younger patients with advanced-stage Hodgkin lymphoma

CHICAGO — Combining brentuximab vedotin with a chemotherapy regimen as first-line therapy conferred an objective response in 88% of younger patients with newly diagnosed advanced-stage classical Hodgkin lymphoma, study results show.

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June 03, 2022
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CAR-T safe, effective for large B-cell lymphoma regardless of race or ethnicity

CAR-T safe, effective for large B-cell lymphoma regardless of race or ethnicity

CHICAGO — Axicabtagene ciloleucel exhibited comparable efficacy and safety for large B-cell lymphoma regardless of patients’ race or ethnicity, according to study results presented at ASCO Annual Meeting.

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June 03, 2022
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Ibrutinib regimen extends PFS for older adults with mantle cell lymphoma

Ibrutinib regimen extends PFS for older adults with mantle cell lymphoma

CHICAGO — A novel first-line regimen significantly improved PFS compared with standard chemoimmunotherapy for older patients with mantle cell lymphoma, according to randomized phase 3 study results presented at ASCO Annual Meeting.

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June 02, 2022
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Watch-and-wait approach remains ‘reasonable’ for some patients with follicular lymphoma

Watch-and-wait approach remains &lsquo;reasonable&rsquo; for some patients with follicular lymphoma

With new developments in the treatment of follicular lymphoma, such as chimeric antigen receptor T-cell therapies, whether the traditional watch-and-wait approach remains acceptable has been thrown into question.

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June 01, 2022
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Safety concerns prompt FDA to withdraw Ukoniq approval for two types of lymphoma

Safety concerns prompt FDA to withdraw Ukoniq approval for two types of lymphoma

The FDA has withdrawn approval of umbralisib for marginal zone lymphoma and follicular lymphoma due to safety concerns, according to an updated drug safety communication.

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May 31, 2022
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FDA approves Kymriah for advanced follicular lymphoma

FDA approves Kymriah for advanced follicular lymphoma

The FDA granted accelerated approval to tisagenlecleucel for treatment of adults with relapsed or refractory follicular lymphoma after two or more lines of systemic therapy.

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