Lupus

SCOTTSDALE, Ariz. — Characteristic microbiome imbalances in patients with lupus could potentially act as both the cause and effect of high lupus disease activity, according to Gregg Silverman, MD, of the New York University School of Medicine.

Rituximab may be a promising option for treatment-refractory childhood-onset lupus erythematosus panniculitis, according to a retrospective, observational case series published in JAMA Dermatology.

Among patients with systemic lupus erythematosus, rash, joint involvement and flares are positively linked with fine particulate matter pollution, according to a spatial-time cluster analysis published in Arthritis & Rheumatology.

MAUI, Hawaii — Evolution of the understanding of systemic lupus erythematosus has shaped guidelines for the disease through the decades, according to a presentation at the 2020 Rheumatology Winter Clinical Symposium.

Low hydroxychloroquine levels in the blood among patients with systemic lupus erythematosus are associated with reported nonadherence, according to a meta-analysis published in Arthritis Care & Research.

Among patients with systemic lupus erythematosus, those with hypertensive disorders of pregnancy are at twice the risk for cardiovascular outcomes as those without such disorders, according to data published in Arthritis Care & Research.

Patients with systemic lupus erythematosus who adhere to antimalarial treatments demonstrate a 39% lower risk for developing type 2 diabetes, compared with those who discontinued, according to findings published in Arthritis Care & Research.

The 2020 Rheumatology Winter Clinical Symposium will feature presentations intended to foster active discussion between those on the dais and those in attendance. The meeting, which is in its 13th year, will take place February 12 to 15, at the Wailea Beach Marriott in Maui, Hawaii.

Principal component analysis can be used to characterize distinctive skin disease patterns using location and lesional data on cutaneous lupus erythematosus skin lesions, according to a cross-sectional study published in Journal of the American Academy of Dermatology.

Among patients with systemic lupus erythematosus, neuropsychiatric events occur most frequently around the time of the initial diagnosis, and are associated with reduced health-related quality of life and excess mortality, according to data published in the Annals of the Rheumatic Diseases.