Lupus
Leflunomide noninferior to azathioprine as lupus nephritis maintenance therapy
Leflunomide is non-inferior to azathioprine in terms of safety and efficacy for lupus nephritis maintenance therapy, according to data published in the Annals of the Rheumatic Diseases.
Higher quality of care fails to improve quality of life in lupus
Patients with systemic lupus erythematosus who report a high quality of care do not necessarily report meaningful clinical differences in quality of life, according to data published in Arthritis Care & Research.
‘Comfort level’ driving divide between rheumatologists, nephrologists in lupus nephritis
Recent data has revealed a growing divide between rheumatologists and nephrologists in their therapeutic choices for patients with lupus nephritis, according to researchers from Spherix Global Insights.
TYK2 inhibitors may offer pathway for more comprehensive inflammation therapy
The emergence of drugs inhibiting the JAK-STAT pathway has culminated in tyrosine kinase 2 inhibitors targeting psoriatic arthritis, lupus and other indications, noted a presenter at the 2022 Association of Women in Rheumatology conference.
Genetics vs. environment: Experts still unraveling links in lupus pathogenesis
Experts are still trying to understand the interplay between genetic and environmental factors in lupus disease pathogenesis, according to a presenter at the 2022 Association of Women in Rheumatology Annual Conference.
No adverse childhood outcomes through 17 years after prenatal hydroxychloroquine exposure
Prenatal exposure to hydroxychloroquine in birthing parents with systemic lupus erythematosus results in no significant adverse outcomes in children from breast feeding through 17 years, according to data published in Rheumatology.
Professor honored for endogenous retrovirus expression research in patients with lupus
The Lupus Research Alliance has awarded the 2022 Lupus Insight Prize to Akiko Iwasaki, PhD, for her work connecting endogenous retroviruses and systemic lupus erythematosus.
Different types of arthritis ‘present very differently’ in synovium, synovial fluid
ORLANDO — Understanding the nature and role of the synovium and synovial fluid is critical to managing various types of arthritis, according to a presenter at the 2022 Rheumatology Nurses Society Annual Conference.
Denial of methotrexate prescriptions post-Roe yields ‘condemnation’
The June 24 Supreme Court decision to overturn Roe vs. Wade continues to reverberate across all of health care, including rheumatology, dermatology and cancer treatment — and in this instance all three at once.
EULAR recommends passive immunization for tetanus in children on B-cell depleting drugs
When a tetanus toxoid vaccination is indicated, pediatric patients treated with B-cell depleting therapy in the past 6 months should receive passive immunization, according to updated EULAR vaccine recommendations.