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Lupus

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November 13, 2022
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Hydroxychloroquine guidelines insufficient to prevent hospitalization for lupus flares

Hydroxychloroquine guidelines insufficient to prevent hospitalization for lupus flares

PHILADELPHIA — In patients with systemic lupus erythematosus, lower doses of hydroxychloroquine increase the risk for hospitalization due to flare, according to data presented at ACR Convergence 2022.

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November 13, 2022
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Severe infection risk for lupus lower with belimumab vs. oral immunosuppressants

Severe infection risk for lupus lower with belimumab vs. oral immunosuppressants

PHILADELPHIA — Patients with non-renal systemic lupus erythematosus who receive belimumab demonstrate a lower risk for severe infection vs. those treated with oral immunosuppressants, according to data presented at ACR Convergence 2022.

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November 13, 2022
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Half of low-grade proteinuria cases in lupus progress to clinical disease within 2 years

Half of low-grade proteinuria cases in lupus progress to clinical disease within 2 years

PHILADELPHIA — Half of patients with systemic lupus erythematosus and new-onset, low-grade proteinuria progress to clinical proteinuria within 2 years, according to results of a study presented at ACR Convergence 2022.

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November 10, 2022
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Proton pump inhibitors associated with signals for drug-induced lupus

Proton pump inhibitors associated with signals for drug-induced lupus

Proton pump inhibitors may be associated with pharmacovigilance signals for the occurrence of drug-induced lupus erythematosus, according to a research letter published in JAMA Dermatology.

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November 07, 2022
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Patients with autoimmune diseases more likely to develop cardiovascular disease

Patients with autoimmune diseases more likely to develop cardiovascular disease

Patients with autoimmune diseases may be at higher risk for cardiovascular disease than patients without autoimmune diseases, according to data published in The Lancet.

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November 04, 2022
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Lupus, coronary artery disease share genetic risk factors; data may lead to early testing

Lupus, coronary artery disease share genetic risk factors; data may lead to early testing

Researchers have identified shared genetic risk factors for systemic lupus erythematosus and coronary artery disease, according to data published in Cell Reports Medicine.

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November 04, 2022
5 min read
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Overcoming physician ‘discomfort’: What rheumatologists need to know about birth control

Overcoming physician ‘discomfort’: What rheumatologists need to know about birth control

Following the Supreme Court’s decision in June overturning Roe v. Wade, communication regarding effective and safe birth control in certain patients, including those with lupus and other rheumatic disease, has become immensely important.

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November 01, 2022
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Chromosomes, hormone changes in cis-, transgender patients drive regulatory T-cell changes

Chromosomes, hormone changes in cis-, transgender patients drive regulatory T-cell changes

Sex-chromosomes and rapid changes in sex hormones during adolescence may drive changes in regulatory T-cell frequency and function, according to data published in The Lancet Rheumatology.

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October 25, 2022
15 min read
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‘Poorly understood’ and rife with mimics: Rheum-neuro diseases require a team approach

‘Poorly understood’ and rife with mimics: Rheum-neuro diseases require a team approach

For all the multitudes of diseases and diversity of organ systems rheumatologists are adept at managing and analyzing, the brain, spinal cord and related neurological conditions are often not among them.

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October 21, 2022
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Immunologic strategies for antiphospholipid syndrome still yield ’not great results’

Immunologic strategies for antiphospholipid syndrome still yield ’not great results’

SAN DIEGO — Primary prevention remains the biggest treatment challenge in antiphospholipid syndrome, according to a speaker at the Congress of Clinical Rheumatology West.

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