Lupus

SAN DIEGO — Patients with lupus who maintained hydroxychloroquine blood levels of 750 ng/ml to 1,200 ng/ml exhibited 71% to 90% lower risk for high lupus disease activity, according to data presented at ACR Convergence 2023.

SAN DIEGO — Improving hydroxychloroquine use and reducing glucocorticoid exposure are among the top priorities of the Healthy People with Lupus 2030 initiative, which aims to address care disparities, said a speaker at ACR Convergence 2023.

SAN DIEGO — A novel combination of elsubrutinib and upadacitinib, called ABBV-599, significantly improves systemic lupus erythematosus disease activity and flares through 48 weeks, according to data presented at ACR Convergence 2023.

SAN DIEGO — Patients with lupus who received sodium-glucose cotransporter-2 inhibitors demonstrated reduced risks for major adverse cardiovascular events and kidney disease, a speaker said at ACR Convergence 2023.

SAN DIEGO — Pregnant patients with very low anti-Ro antibody titers of less than 1,000 units per mL have minimal-to-no risk for fetal atrioventricular block, according to data presented at ACR Convergence 2023.

SAN DIEGO — Obinutuzumab use increases the chances of achieving complete renal response and lowers the risk for kidney-related events and time to flare in lupus nephritis, according to data presented at ACR Convergence 2023.

SAN DIEGO — Pregnant patients with concomitant systemic lupus erythematosus and antiphospholipid syndrome have an 18-fold increased risk for cardiovascular events vs. healthy pregnant controls, said a speaker at ACR Convergence 2023.

A Boston-based biopharma company announced the first participants have been dosed in its phase 1 study to assess safety, tolerability and pharmacokinetics of a novel oral, small molecule therapeutic in healthy adults.

In this episode, we dig through the data of lupus in Africa and speak with experts on the Lupus Gradient, the impact of malaria and what we can learn from it all.

Patients across health care specialties have in recent years come to expect some form of individually tailored care — or precision medicine — as part of their disease management.