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Lupus Nephritis

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May 01, 2024
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FDA approves updated label for Lupkynis with long-term data, new monitoring guidelines

The FDA has approved an updated label for Lupkynis, an oral treatment for active lupus nephritis, that includes long-term safety and tolerability data, and eases the requirement for monthly kidney function assessments.

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April 18, 2024
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Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology

This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin.

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February 29, 2024
2 min read
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FDA clears new drug application for CAR T-cell therapy in SLE with lupus nephritis

The FDA has cleared an investigational new drug application for an allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for the treatment of systemic lupus erythematosus with lupus nephritis, according to the manufacturer.

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February 09, 2024
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KDIGO releases updated guidelines on lupus nephritis

Kidney Disease: Improving Global Outcomes has released a revised clinical practice guideline for the treatment of lupus nephritis.

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January 23, 2024
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FDA grants fast track designation for refractory progressive MS treatment

The FDA has granted fast track designation for an autologous, fully human CD19 chimeric antigen receptor T-cell product candidate to treat those with refractory progressive multiple sclerosis, according to the manufacturer.

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December 14, 2023
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FDA grants fast track designation for novel myasthenia gravis therapeutic

The FDA has granted fast track designation for KYV-101, an autologous, fully human CD19 chimeric antigen receptor T-cell product candidate, to treat myasthenia gravis.

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December 05, 2023
2 min read
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Rose Parade to feature floats promoting transplant and organ donation

An organ procurement organization and a patient support and advocacy group will have floats in the 2024 Tournament of Roses Parade promoting organ donation and to spread awareness about kidney health screening.

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November 28, 2023
3 min read
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EULAR lowers acceptable threshold for daily prednisone dose in lupus maintenance

The acceptable threshold for glucocorticoid use for lupus maintenance therapy should be 5 mg per day prednisone equivalent or less, according to the updated 2023 EULAR recommendations for the management of systemic lupus erythematosus.

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November 16, 2023
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‘Now is the time for action’: ACR program seeks to overcome disparities in lupus care

SAN DIEGO — Improving hydroxychloroquine use and reducing glucocorticoid exposure are among the top priorities of the Healthy People with Lupus 2030 initiative, which aims to address care disparities, said a speaker at ACR Convergence 2023.

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November 15, 2023
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SGLT2 inhibitors have ‘potential role’ in reducing cardiac, renal risks in lupus

SAN DIEGO — Patients with lupus who received sodium-glucose cotransporter-2 inhibitors demonstrated reduced risks for major adverse cardiovascular events and kidney disease, a speaker said at ACR Convergence 2023.

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