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Lupus Nephritis

Clinical Guidance
Lupus
Presentation and Diagnosis

Manifestations, Complications, and Comorbidities of Lupus

Irene Blanco, MD, MS

Systemic lupus erythematosus (SLE) is an exceptionally heterogeneous disease, characterized by a wide spectrum of constitutional and organ-specific manifestations, complications and comorbidities.

Clinical Guidance
Lupus
Overview

Epidemiology of Lupus

Irene Blanco, MD, MS

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

Clinical Guidance
Lupus
Overview

Overview of Lupus

Irene Blanco, MD, MS

Access free, up-to-date clinical references on the Lupus at Healio. We aid in making confident point-of-care decisions.

Clinical Guidance
Lupus
Overview

Types of Lupus

Irene Blanco, MD, MS

Even though each type of lupus has distinguishing characteristics, it is important to note that they may partially overlap in clinical or laboratory features and treatment approaches

News
July 22, 2024
13 min read
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CAR T-cell therapy may be a ‘miracle,’ but it is too soon to say ‘cure’

CAR T-cell therapy may be a ‘miracle,’ but it is too soon to say ‘cure’

It has been at least 2 years since the first cohort of patients with lupus underwent chimeric antigen receptor T-cell treatment, and, at least so far, for every one of them, each new dawn represents another day spent in full remission.

News
July 15, 2024
2 min read
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SGLT2 inhibitors slash risks for lupus nephritis, heart failure in SLE, type 2 diabetes

SGLT2 inhibitors slash risks for lupus nephritis, heart failure in SLE, type 2 diabetes

Treatment with sodium-glucose cotransporter-2 inhibitors significantly lowered risks for lupus nephritis, dialysis and kidney transplant for patients with systemic lupus erythematosus and type 2 diabetes, according to data.

News
June 18, 2024
2 min read
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Patient with lupus treated with KYV-101 CAR T-cell therapy relapses after 5 months

Patient with lupus treated with KYV-101 CAR T-cell therapy relapses after 5 months

A patient with lupus nephritis treated with KYV-101, a chimeric antigen receptor T-cell immunotherapy, saw their disease return 5 months after initially showing a response to the treatment, according to the manufacturer.

News
June 18, 2024
1 min read
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Top in rheumatology: Steroid dosing for lupus nephritis; Benlysta decreases lupus flares

Top in rheumatology: Steroid dosing for lupus nephritis; Benlysta decreases lupus flares

A systemic review and meta-analysis revealed that higher initial glucocorticoid doses improved lupus nephritis treatment response but increased risks for serious infections and mortality.

News
June 13, 2024
2 min read
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Higher steroid dose improves lupus nephritis renal outcomes, raises mortality risk

Higher steroid dose improves lupus nephritis renal outcomes, raises mortality risk

Patients with lupus nephritis who receive higher initial doses of glucocorticoids demonstrate improved renal outcomes, albeit with increased serious infection and mortality risks, according to data published in Arthritis & Rheumatology.

News
May 23, 2024
2 min read
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Serology ‘significantly different’ between membranous vs. proliferative lupus nephritis

Serology ‘significantly different’ between membranous vs. proliferative lupus nephritis

Proteinuria levels are not predictive of membranous lupus nephritis vs. proliferative lupus nephritis, according to data published in Rheumatology.

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