Lupus
Triamcinolone, methylprednisolone avoid prednisone’s fracture risk ‘trap’ in lupus
WASHINGTON — Although even low-dose prednisone significantly increases the risk for fracture in systemic lupus erythematosus, there is no increased risk from intramuscular triamcinolone or intravenous methylprednisolone, said a speaker.
Low Childhood Opportunity Index score may drive inequitable outcomes in pediatric lupus
WASHINGTON — Children with lupus from areas of lower socioeconomic opportunity experience more severe disease complications and poorer outcomes than those from higher opportunity areas, according to data presented at ACR Convergence 2024.
Addressing economic insecurities ‘could improve’ patient reported outcomes in lupus
WASHINGTON — Addressing economic insecurities through a social worker “could improve” physical function and other patient reported outcomes in systemic lupus erythematosus, according to a speaker at ACR Convergence 2024.
Models to predict lupus based on genetics, lifestyle perform ‘very well in all situations’
WASHINGTON — A model predicting the development of systemic lupus erythematosus, based on genetic, lifestyle and environmental factors, was successfully validated in a large cohort, according to data presented at ACR Convergence 2024.
Herpes zoster vaccine effective, shows ‘no signs’ of increased severe flare risk in lupus
WASHINGTON — Herpes zoster vaccination is effective in patients with systemic lupus erythematosus and multiple sclerosis, without increasing the risk for severe lupus flares, according to data presented at ACR Convergence 2024.
Black children with lupus have higher disease activity, less likely to achieve low activity
Black and multiracial children with systemic lupus erythematosus demonstrate higher disease activity and are less likely to achieve low disease activity compared with white children, according to data published in Arthritis Care & Research.
Highest, lowest vitamin D levels predict adverse pregnancy outcomes in lupus
Among pregnant women with systemic lupus erythematosus, those who demonstrate either high or low levels of serum vitamin D are more likely to experience miscarriage, preterm delivery and other adverse outcomes, according to data.
FDA clears way for trial of novel bispecific T-cell engager for lupus
The FDA has cleared an investigational new drug application allowing a novel bispecific T-cell engager to begin a phase 1 trial in patients with active, moderate-to-severe systemic lupus erythematosus, according to a press release.
Placenta lesions common in lupus pregnancies with small for gestational age infants
Among pregnancies in patients with systemic lupus erythematosus, those with small for gestational age infants were significantly more likely to demonstrate increased perivillous fibrin deposition in the placenta, according to data.
Repeat kidney biopsies may help manage lupus nephritis flares
Repeat kidney biopsies may help patients with lupus nephritis manage disease flares, particularly those who transition between proliferative and non-proliferative disease classes, data from a racially diverse study cohort show.