Lung Transplant

Lung transplant recipients lived for a longer time if they received lungs from a donor cared for in a hospital-based vs. independent donor care unit, according to results published in JAMA Network Open.

Following transplantation, recipients with a lung from a donor who had tobacco smoke exposure did not have higher mortality, according to results published in American Journal of Respiratory and Critical Care Medicine.

In an effort to help more patients in need of lungs receive a transplant, researchers are considering a technique that pumps blood to a donor’s organs and re-perfuses the lungs, according to a press release.

Over recent years, the use of robotics for diagnosing people with lung cancer has been seen as promising, and the FDA even cleared a robotic navigated bronchoscopy system in 2023 to locate pulmonary lesions.

Storing donor lungs in a controlled hypothermic storage device with a total ischemic time of more than 15 hours “appears to be safe” in adult recipients, according to results published in Journal of Heart and Lung Transplantation.

Race-specific vs. race-neutral lung function equations misclassified more patients with pulmonary fibrosis eligible for trials, therapy and transplantation referral, according to results published in Annals of the American Thoracic Society.

Researchers found that risk factors of invasive fungal infections for lung transplant recipients receiving universal antifungal prophylaxis varied in terms of early and late infection and invasive mold- and candidiasis-type infections.

Lung transplant recipients with extreme low or high BMIs had heightened risks for death due to acute respiratory failure and chronic lung allograft dysfunction, according to results published in Annals of the American Thoracic Society.

Patients with bronchopulmonary dysplasia who received a lung transplant showed survival rates comparable to those of transplant recipients with other lung diseases, according to results published in CHEST.

Since its first transplant in March 2022, the Mount Sinai Lung Transplantation Program has performed a total of 35 lung transplants with a 180-day survival rate of 88.6%, according to a presentation.