Lung Function
Lung function deficits in preterm-born infants improved over time
Preterm-born survivors had decreased lung function, especially those with bronchopulmonary dysplasia, compared with term-born infants, but decreased values improved over time, according to research published in JAMA Pediatrics.
Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis
Inhaled hypertonic saline treatment for 48 weeks led to positive effects on structural lung changes in young children with cystic fibrosis compared with isotonic saline, researchers reported in The Lancet Respiratory Medicine.
Early follow-up post-discharge may cut readmissions for patients with complex conditions
Early physician follow-up with a comprehensive transitional care strategy and effective chronic disease management after discharge was associated with reduced 90-day readmissions among patients with COPD and other complex conditions.
AI tool shows promise for detection of incidental PE
An artificial intelligence tool for detecting incidental pulmonary embolus on conventional contrast-enhanced chest CT had high negative predictive value and moderate positive predictive value for detection, researchers reported.
Initiating single-inhaler triple therapy for COPD improved persistence, outcomes vs. multiple inhalers
Initiating single-inhaler triple therapy for COPD, compared with multiple-inhaler triple therapy, resulted in improved persistence, which led to reductions in mortality, exacerbations and health care resource use in patients with COPD.
Proactive, virtual intervention improves quality of life after discharge for COPD exacerbation
A pragmatic health system-level intervention improved quality of life for patients discharged after COPD exacerbation but failed to reduce 180-day readmission or mortality, researchers reported.
Impaired exercise ventilatory efficiency contributes to dyspnea, exercise limitation in COPD
Impaired exercise ventilatory efficiency above the upper limit of normal was associated with a greater dyspnea burden and low peak VO2 among never smokers and smokers with or without COPD, researchers reported.
FDA approves nitric oxide generator to treat neonates with hypoxic respiratory failure
Beyond Air has received FDA approval for nitric oxide generator and delivery system to treat term and near-term neonates with hypoxic respiratory failure
Study identifies subphenotypes of cystic fibrosis pulmonary exacerbations
A new study published in Annals of the American Thoracic Society highlighted subphenotypes of cystic fibrosis pulmonary exacerbations and differences in biomarker profiles, clinical presentation and outcomes.
Chronic bronchial infection associated with lung function decline in COPD
Chronic bronchial infection by any pathogenic microorganism, and particularly with Pseudomonas aeruginosa, was identified as a risk factor for lung function decline among patients with COPD, researchers reported.