Lung Function

Fetal growth restriction impaired intrauterine lung development and led to reduced measures of lung function later in life, according to a study published in Annals of the American Thoracic Society.

Researchers found increased amounts of retained dust in the lung tissue of previously deployed military personnel with confirmed lung injury, according to a presenter at the 2022 Geological Society of America Meeting.

Lumacaftor/ivacaftor appeared safe and well tolerated for up to 24 weeks in children aged 1 year to younger than 2 years homozygous for F508del-CFTR, according to a study in American Journal of Respiratory and Critical Care Medicine.

Patients with asthma and insulin resistance had lower and faster loss of lung function, as well as suboptimal responses to asthma treatments, according to a study published in American Journal of Respiratory and Critical Care Medicine.

Patients with COPD experienced early, but modest and nonpersistent, reductions in lung function during treatment with metoprolol, according to a post-hoc analysis of the BLOCK COPD study in The Annals of the American Thoracic Society.

Among the top takeaways from the CHEST 2022 Annual Meeting, held Oct. 16 to 19 in Nashville, Tennessee, were diversity in content and speakers, addressing disparities and new initiatives, according to Subani Chandra, MD, FCCP.

Photon-counting detector CT found more subtle lung abnormalities that may indicate irreversible lung fibrosis in symptomatic patients following COVID-19 infection than conventional CT, according to a study published in Radiology.

The FDA granted orphan drug designation to ifenprodil for the treatment of patients with idiopathic pulmonary fibrosis, according to a press release from the drug’s manufacturer.

Individuals who smoked marijuana were more likely to have emphysema, airway changes and gynecomastia than tobacco-only smokers and nonsmokers, according to a study published in Radiology.

Among patients previously hospitalized with COVID-19, researchers estimated that up to 11% had fibrotic patterning, according to a study published in American Journal of Respiratory and Critical Care Medicine.