Lung Cancer

Death due to a second primary cancer occurred nearly twice as often among adolescent and young adult cancer survivors compared with the general population, according to study results published in Journal of the National Cancer Institute.

Healio spoke with Rebecca L. Siegel, MPH, senior scientific direct of surveillance research at the American Cancer Society, to learn more about earlier detection of lung cancer and how it has helped patients increase their odds of survival and helped clinicians effectively treat their patients.

Incidental respiratory disease-related findings, including emphysema and reticular opacities, observed on low-dose CT lung cancer screenings were common and associated with increased mortality, researchers reported.

In her new role as CEO of the International Association for the Study of Lung Cancer, or IASLC, Karen Kelly, MD, has seen her reach as a leader expand from local to global.

In this edition, a phase 3 trial of a regimen for small cell lung cancer misses its co-primary endpoint; obesity and pulmonary function may identify the need for home oxygen after lung cancer surgery; a study finds that lung cancer screening is less common among those most likely to benefit from it; and more.

Men, smokers and younger patients with non-small cell lung cancer all appeared to derive more benefit from immunotherapy, according to a systematic review published in JNCI Cancer Spectrum.

A novel PD-1/CTLA-4 bispecific checkpoint inhibitor demonstrated antitumor activity and tolerability among patients with advanced solid tumors, according to study results.

The FDA granted priority review to trastuzumab deruxtecan for treatment of adults with unresectable or metastatic HER2-mutated non-small cell lung cancer, according to a press release from the agent’s manufacturer.

Plinabulin demonstrated similar efficacy to pegfilgrastim for the prevention of chemotherapy-induced neutropenia, according to results of a randomized phase 3 study published in JAMA Network Open.

Patients with non-small cell lung cancer exhibited less depression and anxiety when receiving treatment during the COVID-19 pandemic than healthy individuals, according to a study in Journal of National Comprehensive Cancer Network.