Loyola University
Patients with Medicaid have low functional outcome scores after shoulder arthroplasty
Patients with Medicaid are younger, have more debilitating disease, and lower preoperative and postoperative American Shoulder and Elbow Surgeons scores after shoulder arthroplasty compared with those with private insurance and Medicare.
T-cell Responses to Concurrent HIV and Herpesvirus Infections
An observational, prospective cohort study to discover new information about how HIV and herpes viruses interact with the immune system, with a goal of learning more about how T cells in the immune system respond to and fight off long-term (chronic) viruses, in order to improve medical care in the future.
TCR-engineered T Cells in Solid Tumors (ACTengine)
NY-ESO-1 TCR Engineered T Cell and HSC After Melphalan Conditioning Regimen in Treating Participants with Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Phase 1, open-label study evaluating the safety and efficacy of adoptive transfer of autologous NY-ESO-1 CD8-TCR engineered T cells and NY-ESO-1 CD4-TCR engineered hematopoietic stem cells after a myeloablative conditioning regimen, with administration of IL-2 in patients with relapsed or treatment-refractory ovarian, fallopian tube or primary peritoneal cancer.
HA-1 T TCR T Cell Immunotherapy for the Treating of Patients with Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
Phase 3 trial assesses intraoperative radiotherapy for glioblastoma
An international randomized phase 3 trial is underway to evaluate the efficacy of intraoperative radiotherapy for patients with glioblastoma multiforme.
Black women at higher risk for breast cancer recurrence, mortality
SAN ANTONIO — Black women appeared to be at higher risk for breast cancer recurrence and overall mortality than white women, despite receiving similar treatment based on their 21-gene recurrence scores, according to results of the phase 3 TAILORx trial presented at San Antonio Breast Cancer Symposium.
Guest commentary: Weeding out the ‘good’ and ‘bad’ of probiotics for our patients
In this exclusive Guest Commentary in cooperation with the American Gastroenterological Association, Gail Hecht, MD, MS, AGAF, offers advice on how health care professionals can best discuss probiotics with their patients.
Careful planning needed in cataract cases with inflammation
Inflammation is a dreaded obstacle and potential complication of surgical procedures in general and can be sight-threatening in procedures such as cataract surgery. With regard to cataract surgery, even with modern-day technological advances and improved surgical procedures, inflammation is still a potential complication that needs to be addressed. Such ocular inflammation can be divided into three phases, preoperative, intraoperative and postoperative, and the surgeon needs to address all three periods to provide a comprehensive, optimal outcome. Additionally, potential intraoperative and postoperative complications should be routinely discussed with high-risk patients.