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Lorundrostat

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January 15, 2025
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FDA clears investigational new drug application for lorundrostat in OSA, hypertension

The FDA approved the phase 2 Explore-OSA trial set to assess the highly selective aldosterone synthase inhibitor, lorundrostat, in adults with obstructive sleep apnea and hypertension, according to a press release.

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November 02, 2023
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Post-hoc analysis supports association of BMI, reduced blood pressure with lorundrostat

PHILADELPHIA — Obesity-associated dysregulated aldosterone is an endotype predictive of response to lorundrostat for patients with uncontrolled or treatment-resistant hypertension, according to data presented at ASN Kidney Week.