Liver Transplant
The leading edge: New therapies redefine PBC treatment landscape
Recent advancements have been made in the treatment of primary biliary cholangitis, particularly for patients who do not respond adequately to first-line treatment.
Kidney transplant outcomes similar with organs from deceased donors with, without HIV
For organ transplant recipients with HIV, kidneys from deceased donors with HIV are noninferior those from donors without HIV, according to data from a U.S. multicenter observational trial.
Waitlist priority, quality donors tied to better outcomes in pediatric acute liver failure
Over three decades, changes to organ allocation policies were associated with reduced waitlist mortality and increased rates of liver transplant among children with pediatric acute liver failure, according to research in JAMA Surgery.
Immunotherapy may make transplant possible in late-stage liver cancer
Immunotherapy treatment may make liver transplant viable for patients with later-stage hepatocellular carcinoma provided they adhere to a 3-month waiting period, according to study results.
Competing-risk model provides more accurate estimate of transplant waiting time
A simple median waiting time that did not account for censoring, death and other competing events underestimated time to organ transplantation by up to 61% compared with a competing-risk model, according to a study conducted in Switzerland.
Younger age, prior relapse among predictors of alcohol use after liver transplant in ALD
Researchers have identified additional predictors of relapse in patients undergoing liver transplant for alcohol-related liver disease, including younger age and prior relapse, which differ from components of current prediction scores.
Q&A: ‘Make them explain’: How a patient’s self-advocacy finally led to a PBC diagnosis
When Tiffany McLellan was 18 years old, she was diagnosed with an ulcer in her digestive tract. She found relief with antacids for almost 2 years, but after her son was born, she started experiencing digestive issues and pain again.
HHS proposes rule change for HIV-positive organ recipients
Patients with HIV in need of a kidney or liver transplant may no longer be required to participate in a clinical study to receive an organ from a donor with HIV, according to a proposed federal rule change published in the Federal Register.
GLP-1RA use linked to lower risk for cirrhosis, mortality in MASLD with diabetes
Use of glucagon-like peptide-1 receptor agonists was associated with a reduced risk for progression to cirrhosis and other complications in patients with metabolic dysfunction-associated steatotic liver disease and diabetes, data showed.
ZIP code, social vulnerability affect access to liver transplant in alcohol-related disease
Most recipients of early liver transplant for severe alcohol-related liver disease live in close proximity to transplant centers, which are more likely to be in socially advantaged areas, according to research in Gastro Hep Advances.