Liver Transplant

Normothermic machine perfusion was linked to significant improvements in liver transplant clinical outcomes and reduced hospital resource use, especially among patients who received donation after circulatory death allografts, data show.

The AHFIRM trial did not demonstrate a beneficial effect of larsucosterol on 90-day mortality or the need for liver transplant among patients with severe alcohol-associated hepatitis, or AH, according to a study published in NEJM Evidence.

There are approximately 100,000 alcohol-related cancer cases annually in the U.S. and 20,000 deaths due to alcohol-related cancer, according to an HHS press release.

A new model has projected a substantial rise in the burden of metabolic dysfunction-associated steatotic liver disease in the U.S. by 2050, which could be minimized by effective preventive and management strategies, researchers wrote.

The success of Mayo Clinic’s first paired living-donor liver transplantation may pave the way for expanded access and more “timely transplant” for patients in need, Timucin Taner, MD, PhD, told Healio.

The FDA has issued a safety alert warning that obeticholic acid carries an increased risk for “serious liver injury” among patients with primary biliary cholangitis, even those without advanced cirrhosis.

SAN DIEGO — Waitlist mortality and liver transplant rates for women appear to more closely align with rates for men after the implementation of MELD 3.0, according to late-breaking data presented at The Liver Meeting.

HHS adopted a final rule eliminating the requirement that patients with HIV in need of a kidney or liver transplant participate in a clinical study to receive an organ from a donor with HIV, according to an agency press release.

SAN DIEGO — Patients with diabetes who were prescribed glucagon-like peptide-1 receptor agonists had lower odds of metabolic dysfunction-associated steatotic liver disease after liver transplantation, noted a presenter at The Liver Meeting.

PHILADELPHIA — Liver transplant recipients who lived in counties with limited access to healthy food were at higher risk for developing diabetes following transplantation, according to data presented at the ACG Annual Scientific Meeting.