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Liver Steatosis

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June 01, 2024
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Sedentary children risk liver disease in young adulthood

BOSTON — Accumulating sedentary time during childhood was associated with increased risk for liver disease in young adulthood, but boosting light physical activity may lessen the risk, according to data presented at ENDO 2024.

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April 01, 2024
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Low-dose aspirin ‘significantly’ reduced hepatic fat in MASLD by more than 10% vs. placebo

Daily low-dose aspirin “significantly reduced” hepatic fat quantity at 6 months compared with placebo among patients with metabolic dysfunction-associated steatotic liver disease, according to preliminary trial results published in JAMA.

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February 15, 2024
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FDA grants 510(k) clearance to Nanox AI software to assess ‘early signs’ of fatty liver

The FDA has granted 510(k) clearance to Nanox’s HealthFLD artificial intelligence software to aid clinicians in the detection of fatty liver associated with hepatic steatosis, according to a company press release.

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November 29, 2022
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Obesity predicts liver disease for children with type 1 diabetes

Clinical and imaging findings of children with type 1 diabetes and obesity were similar to those for children without diabetes with similar degrees of obesity, according study results published in Journal of Diabetes and its Complications.

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December 07, 2021
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Children, adolescents with NAFLD see decrease in liver steatosis, fibrosis with lifestyle therapy

Intensive lifestyle therapy in children and adolescents with nonalcoholic fatty liver disease led to significant weight loss and improvements in liver steatosis and fibrosis, according to study results.

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December 01, 2021
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Gastric bypass, sleeve gastrectomy ‘substantially’ reduce liver fat in type 2 diabetes

Roux-en-Y gastric bypass and sleeve gastrectomy are equally effective at reducing hepatic steatosis, with an almost complete clearance of liver fat 1 year after the surgical procedures, according to data from a single-center study.

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November 16, 2021
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Pegbelfermin improves markers of fibrosis in NASH

Pegbelfermin was safe and effective in improving markers of steatosis, fibrosis and inflammation among patients with nonalcoholic steatohepatitis with stage 3 fibrosis, according to a presentation at The Liver Meeting Digital Experience.

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June 25, 2021
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Low-carb high-fat, intermittent fasting diets reduce more hepatic steatosis in NAFLD

Researchers saw higher reduction in steatosis and body weight with the low-carb high-fat and 5:2 diets compared with the standard of care in patients with nonalcoholic fatty liver disease, according to a presentation at the International Liver Congress.

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November 01, 2019
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FDA grants fast track designation to FXR agonist for NASH

The FDA granted fast track designation to Terns Pharmaceuticals for TERN-101, an investigational farnesoid X receptor being evaluated for nonalcoholic steatohepatitis, according to a press release.

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September 17, 2019
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Poxel NASH candidate moves into phase 1b

Poxel SA announced the initiation of a phase 1b trial designed to investigate PXL065 for the treatment of nonalcoholic steatohepatitis in patients without cirrhosis, according to a press release.

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