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Liver Disease

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August 14, 2024
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FDA approves Gilead’s Livdelzi for treatment of primary biliary cholangitis

FDA approves Gilead’s Livdelzi for treatment of primary biliary cholangitis

Gilead’s Livdelzi, a selective peroxisome proliferator-activated receptor delta agonist, has received accelerated FDA approval for the treatment of primary biliary cholangitis, according to a company release.

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July 26, 2024
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‘It’s time for action’: World Hepatitis Day calls to end an ‘entirely preventable disease’

‘It’s time for action’: World Hepatitis Day calls to end an ‘entirely preventable disease’

Every year on July 28th, clinicians and researchers recognize World Hepatitis Day to bring awareness to one of the world’s deadliest but preventable viruses and continue efforts to meet the global goal of eliminating viral hepatitis by 2030

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July 25, 2024
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Up-to-date HCC screening after HCV cure improves survival in patients with cirrhosis

Up-to-date HCC screening after HCV cure improves survival in patients with cirrhosis

Remaining current on screening for hepatocellular carcinoma correlated with a “survival benefit” in older adults with hepatitis C virus-related cirrhosis who achieved viral cure but later developed HCC, according to researchers.

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July 22, 2024
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Fazirsiran lowers serum, liver concentrations of Z-AAT in alpha-1 antitrypsin deficiency

Fazirsiran lowers serum, liver concentrations of Z-AAT in alpha-1 antitrypsin deficiency

In a dose-dependent manner, fazirsiran reduced serum and liver concentrations of Z-AAT and also improved histological measures in patients with homozygous ZZ alpha-1 antitrypsin deficiency-associated liver disease, according to data.

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July 15, 2024
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VIDEO: GLP-1 use for MASH is ‘not black and white’; best approach may lie in the gray

VIDEO: GLP-1 use for MASH is ‘not black and white’; best approach may lie in the gray

In a Healio video exclusive, Edward V. Loftus Jr., MD, noted that, despite the boom in glucagon-like peptide-1 agonists for diabetes and weight loss, its role in the treatment of liver disease is still up for debate.

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July 05, 2024
3 min read
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Statin use when not indicated for certain strokes could cause adverse events

Statin use when not indicated for certain strokes could cause adverse events

Statin initiation in patients with stroke etiologies not indicated for secondary prevention with statin therapy could hypothetically cause thousands of adverse events every year, according to a new meta-analysis published in Stroke.

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July 03, 2024
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ACG recommends full patient workup, evaluation to differentiate focal liver lesions

ACG recommends full patient workup, evaluation to differentiate focal liver lesions

In a new clinical practice guideline, the ACG has provided evidence-based recommendations for the diagnosis and management of the most common focal liver lesions among individuals without known liver disease.

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June 20, 2024
4 min read
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‘Distressing’ data show LGBTQ+ cancer survivors at higher risk for chronic health issues

‘Distressing’ data show LGBTQ+ cancer survivors at higher risk for chronic health issues

Cancer survivors who identify as LGBTQ+ had increased risk for numerous chronic health issues compared with non-LGBTQ+ survivors, results from a survey study showed.

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June 11, 2024
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VIDEO: Bulevirtide remains ‘efficacious, well tolerated’ in chronic hepatitis D at 2 years

VIDEO: Bulevirtide remains ‘efficacious, well tolerated’ in chronic hepatitis D at 2 years

In a Healio video exclusive, Anu Osinusi, MD, MPH, reported long-term bulevirtide monotherapy 2 mg and 10 mg remained safe and effective for chronic hepatitis D virus with improved biochemical, fibrosis and virologic markers at 144 weeks.

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June 05, 2024
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GLP-1 receptor agonists ‘have changed the playing field’ in pediatric MASLD

GLP-1 receptor agonists ‘have changed the playing field’ in pediatric MASLD

WASHINGTON — Glucagon-like peptide-1 receptor agonists significantly reduced alanine aminotransferase levels in pediatric metabolic dysfunction-associated steatotic liver disease, especially those with type 2 diabetes, researchers reported.

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